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  4. Recombinant Drosophila melanogaster Short neuropeptide F (sNPF)

Recombinant Drosophila melanogaster Short neuropeptide F (sNPF)

  • 中文名称：
    黑腹果蝇sNPF重组蛋白
  • 货号：
    CSB-YP894700DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇sNPF重组蛋白
  • 货号：
    CSB-EP894700DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇sNPF重组蛋白
  • 货号：
    CSB-EP894700DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇sNPF重组蛋白
  • 货号：
    CSB-BP894700DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇sNPF重组蛋白
  • 货号：
    CSB-MP894700DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    sNPF
  • Uniprot No.：
  • 别名：
    sNPF; CG13968; Short neuropeptide F [Cleaved into: sNPF-associated peptide; sNPF-AP); sNPF peptide 2; sNPF-2); sNPF peptide 3; sNPF-3); sNPF peptide 4; sNPF-4); RLRF peptide 1; RLRF peptide 2]
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    86-96
  • 氨基酸序列
    AQRSP SLRLRF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in controlling food intake and regulating body size.
  • 基因功能参考文献：
    1. Light and the neuropeptides PDF and sNPF act dynamically at distinct hubs of the circadian neural circuit to produce multiple suppressive events that create the proper tempo and sequence of circadian pacemaker neuronal activities. PMID: 28552314
    2. Findings indicate that short neuropeptide F (sNPF) and corazonin (CRZ) co-released from a small set of neurons regulate insulin-producing cells (IPCs) stress resistance and metabolism. PMID: 22828865
    3. Loss of function of sNPF and sNPFR1 also elevated sleep. PMID: 23796436
    4. Here we show that a neuropeptide precursor gene encoding four types of short neuropeptide F (sNPF) is required in the Kenyon cells for appetitive olfactory memory. PMID: 23516298
    5. Different layers of the fan-shaped body sNPFR1 PMID: 22361394
    6. sNPF is expressed in the nervous systems to control food intake and regulate body size in Drosophila melanogaster PMID: 15385546
    7. Results show that Drosophila short neuropeptide F, an orthologue of mammalian neuropeptide Y, and sNPF receptor sNPFR1 regulate expression of insulin-like peptides. PMID: 18344986
    8. Data show Drosophila brain expressing short neuropeptide F transcript and short neuropeptide F peptide. Most of these PMID: 18803813
    9. We have demonstrated here that subsets of Drosophila lateral clock neurons are heterogeneous with respect to expression of neuroactive compounds, including ion transport peptide and short neuropeptide F PMID: 19565664
    10. These results indicate that sNPF1 and sNPF2 peptides processed from the sNPF precursor are sufficient for regulating body growth through the ERK-insulin pathway in Drosophila. PMID: 19619547

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    NPY family
  • 组织特异性：
    Stage 17 embryos show expression in the two brain hemispheres (neural cells located in the dorsal posterior region), the connected ventral ganglion (pairs of neural cells along the ventral midline) and the peripheral nervous system (expressed in the anten
  • 数据库链接：

    KEGG: dme:Dmel_CG13968

    STRING: 7227.FBpp0080859

    UniGene: Dm.5706