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  4. Recombinant Drosophila melanogaster Torso-like protein (tsl)

Recombinant Drosophila melanogaster Torso-like protein (tsl)

  • 中文名称：
    黑腹果蝇tsl重组蛋白
  • 货号：
    CSB-YP331209DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇tsl重组蛋白
  • 货号：
    CSB-EP331209DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇tsl重组蛋白
  • 货号：
    CSB-EP331209DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇tsl重组蛋白
  • 货号：
    CSB-BP331209DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇tsl重组蛋白
  • 货号：
    CSB-MP331209DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    tsl
  • Uniprot No.：
  • 别名：
    tsl; CG6705; Torso-like protein
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    20-353
  • 氨基酸序列
    G RRESQLRIGK AINIFLRYGY LGISMRVIPL NDNSEPDRWV FKEPTKNIYR NLSGLAESHE DTTPGIFHGD FHMEFCENRR QLFQAYFRDF SIERMDKPWE AFTGGWFPDN AAKKLGINTS FIQGDYSYVL VRVVRFRETG RLNAEIPVHQ PLEPDVRSRM DQLQIGNITS AVRFMEDVGT HYVNSYTTGN SLYQVFVYSR KNYSMIKERI KSKGLNGLSK LDLYNYFAPW FAAHLGQIRS ASANATVERW ARRKLQYEYY VVKYVTLLKL HGNSTLLRSL DSLLGNDAIL QLDLKSLKPI FREEPEKESW YHEVLDNNVK LWELNMPQSH PTR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable ligand that binds to the torso receptor. Implicated in a receptor tyrosine kinase signaling pathway that specifies terminal cell fate.
  • 基因功能参考文献：
    1. Recent studies show that Torso-like (Tsl), the only MACPF member that has been identified, has multiple roles in development. PMID: 28506893
    2. tsl null mutants display a ventral cuticular hole phenotype. Tsl controls Rho1-mediated apical constriction via Fog. PMID: 28495958
    3. Together these data suggest that Torso-like plays an important role in controlling the development of the Drosophila cellular immune system PMID: 27535927
    4. Tsl accumulates at the embryonic plasma membrane, even in the absence of the Tor receptor. PMID: 25758463
    5. Nasrat and Polehole are essential for extracellular accumulation of Torso-like, a factor secreted during oogenesis that initiates Torso receptor activation (Polehole protein) PMID: 11959840
    6. The torso-like gene (tsl) is required to trigger Torso receptor tyrosine kinase activation in the Drosophila embryo. PMID: 17595301

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  • 亚细胞定位：
    Secreted. Note=Is a component of the vitelline membrane (VM, the inner layer of the eggshell).
  • 组织特异性：
    Restricted to specialized categories of follicle cells localized at the poles of the egg chamber.
  • 数据库链接：

    KEGG: dme:Dmel_CG6705

    STRING: 7227.FBpp0083562

    UniGene: Dm.2380