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  4. Recombinant Emericella nidulans DNA-binding protein creA (creA)

Recombinant Emericella nidulans DNA-binding protein creA (creA)

  • 中文名称：
    Recombinant Emericella nidulans DNA-binding protein creA(creA),Yeast
  • 货号：
    CSB-YP312488EKF
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Emericella nidulans DNA-binding protein creA(creA),Yeast
  • 货号：
    CSB-EP312488EKF
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Emericella nidulans DNA-binding protein creA(creA),Yeast
  • 货号：
    CSB-EP312488EKF-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Emericella nidulans DNA-binding protein creA(creA),Yeast
  • 货号：
    CSB-BP312488EKF
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Emericella nidulans DNA-binding protein creA(creA),Yeast
  • 货号：
    CSB-MP312488EKF
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    creA
  • Uniprot No.：
  • 别名：
    creA; AN6195DNA-binding protein creA; Carbon catabolite repressor A
  • 种属：
    Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-416
  • 氨基酸序列
    MPQPGSSVDF SNLLNPQNNT AIPAEVSNAT ASATMASGAS LLPPMVKGAR PAAEEARQDL PRPYKCPLCE RAFHRLEHQT RHIRTHTGEK PHACQFPGCS KRFSRSDELT RHSRIHNNPN SRRGNKAQHL AAAAAAAAAN QDGSAMANNA GSMMPPPSKP ITRSAPVSQV GSPDISPPHS FSNYANHMRS NLSPYSRTSE RASSGMDINL LATAASQVER DESFGFRSGQ RSHHMYGPRH GSRGLPSLSA YAISHSMSRS HSHEDEDSYA SHRVKRSRPN SPNSTAPSSP TFSHDSLSPT PDHTPLATPA HSPRLKPLSP SELHLPSIRH LSLHHTPALA PMEPQAEGPN YYNPNQPHVG PSISDIMSRP EGAQRKLPIP QVPKVAVQDM LNPSGFTSVS SSTANSVAGG DLAERF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter. Plays also a role in response to carbon starvation and the control of extracellular proteases activity.
  • 基因功能参考文献：
    1. CreA is not a direct target of CreB, and nor are proteins that form part of a stable complex with CreA a target of CreB. These results open up new questions regarding the molecular mechanism of CreA repressing activity, and how the ubiquitination pathway involving CreB interacts with this regulatory network PMID: 27878624
    2. overview of genes either affected directly or indirectly by CreA, genes affected by the carbon source and genes affected by both CreA as well as the carbon source PMID: 16698295
    3. Mutations in the creA, creB and creC genes increased extracellular protease levels in medium lacking a carbon source suggesting that they may have a role in the response to carbon starvation as well as carbon catabolite repression. PMID: 18512059
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    CreA/MIG C2H2-type zinc-finger protein family
  • 数据库链接：

    KEGG: ani:AN6195.2

    STRING: 162425.CADANIAP00006813