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  4. Recombinant Escherichia coli ATP-dependent Clp protease adapter protein ClpS (clpS),Escherichia Coli

Recombinant Escherichia coli ATP-dependent Clp protease adapter protein ClpS (clpS),Escherichia Coli

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  • 中文名称：
    Recombinant Escherichia coli ATP-dependent Clp protease adapter protein ClpS(clpS),Escherichia Coli
  • 货号：
    CSB-EP359175ENV
  • 规格：
    ￥2328
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    clpS
  • Uniprot No.：
  • 别名：
    clpS; yljA; b0881; JW0865ATP-dependent Clp protease adapter protein ClpS
  • 种属：
    Escherichia coli (strain K12)
  • 蛋白长度：
    full length protein
  • 来源：
    E.coli
  • 表达区域：
    1-106
  • 氨基酸序列
    MGKTNDWLDF DQLAEEKVRD ALKPPSMYKV ILVNDDYTPM EFVIDVLQKF FSYDVERATQ LMLAVHYQGK AICGVFTAEV AETKVAMVNK YARENEHPLL CTLEKA
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal His-tagged and C-terminal Myc-tagged/N-terminal His-SUMO-tagged and C-terminal Myc-tagged/N-terminal His-B2M-tagged and C-terminal Myc-tagged/N-terminal His-GST-tagged and C-terminal Myc-tagged/N-terminal His-tagged/N-terminal His-SUMO-tagged/N-terminal His-B2M-tagged/N-terminal His-GST-tagged/N-terminal GST-tagged/Tag-Free
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
  • 基因功能参考文献：
    1. Between the halves of the clpA pseudo-dimer is a large flexible acidic loop that becomes better ordered upon binding of the small adaptor protein, ClpS PMID: 15037248
    2. the ClpAP-specific adaptor, ClpS, is essential for degradation of N-end rule substrates by ClpAP PMID: 16467841
    3. ClpAP recognizes N-end rule substrates directly, whereas ClpS modulates this degradation pathway. PMID: 17322400
    4. ClpS is an integral and essential component of the N-end rule pathway. PMID: 19317833
    5. The data suggest that ClpS has been optimized for the binding and delivery of N-degrons containing an N-terminal Phe or Leu. PMID: 19373253
    6. ClpS selectively binds N-terminal destabilizing residues and targets them for degradation by the ClpAP complex resulting in carefully regulated proteolysis PMID: 16467841

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  • 蛋白家族：
    ClpS family
  • 数据库链接：

    KEGG: ecj:JW0865

    STRING: 316385.ECDH10B_0951