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  4. Recombinant Escherichia coli Cell division protein FtsL (ftsL), partial

Recombinant Escherichia coli Cell division protein FtsL (ftsL), partial

  • 中文名称：
    大肠杆菌ftsL重组蛋白
  • 货号：
    CSB-YP360140ENV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大肠杆菌ftsL重组蛋白
  • 货号：
    CSB-EP360140ENV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大肠杆菌ftsL重组蛋白
  • 货号：
    CSB-EP360140ENV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大肠杆菌ftsL重组蛋白
  • 货号：
    CSB-BP360140ENV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大肠杆菌ftsL重组蛋白
  • 货号：
    CSB-MP360140ENV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ftsL
  • Uniprot No.：
  • 别名：
    ftsL; mraR; yabD; b0083; JW0081Cell division protein FtsL
  • 种属：
    Escherichia coli (strain K12)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. Can also mediate Zn(2+)-sensitivity probably by increasing the permeability of the inner membrane.
  • 基因功能参考文献：
    1. the data suggest that FtsL forms an uninterrupted helix across the two regions and that the integrity of this helix is indispensable for the function of the complex. The FtsL helix is thus a candidate for acting as a potential mechanical connection to communicate conformational changes between periplasmic, membrane, and cytoplasmic regions. PMID: 29233891
    2. results support a model in which FtsL, along with its partners FtsB and FtsQ, function as part of a sensing mechanism that promotes the onset of cell wall remodeling processes. PMID: 25496050
    3. A structural model was developed for the periplasmic part of the FtsB/FtsL/FtsQ complex. PMID: 21672257
    4. The s demonstrate that the leucine zipper-like (LZ) motifs, located in the periplasmic domain of FtsL and FtsB, are required for an optimal interaction between these two essential proteins. PMID: 21784946
    5. ftsL can confer a metal-ion sensitive phenotype and trans-membrane cysteine residues play a role in FtsL function in elevated metal-ion concentrations. PMID: 21708137
    6. Study find that, as with FtsB, the C terminus of FtsL is required for the interaction of FtsQ with the FtsB/FtsL subcomplex while the cytoplasmic domain of FtsL is involved in recruitment of the downstream division proteins. PMID: 20363951
    7. FtsL is associated in a hierarchical set of protein complexes and its assembly can occur independently of 'upstream' proteins. PMID: 16824093

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  • 亚细胞定位：
    Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure. Localization requires FtsZ, FtsA, ZipA, FtsK, FtsQ and FtsB, but not FtsI and FtsN. Localization of FtsB and FtsL is codependent.
  • 蛋白家族：
    FtsL family
  • 数据库链接：

    KEGG: ecj:JW0081

    STRING: 316385.ECDH10B_0065