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  4. Recombinant Escherichia coli Putative acyl-CoA dehydrogenase AidB (aidB)

Recombinant Escherichia coli Putative acyl-CoA dehydrogenase AidB (aidB)

  • 中文名称：
    Recombinant Escherichia coli Putative acyl-CoA dehydrogenase AidB(aidB),Yeast
  • 货号：
    CSB-YP329241ENV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Escherichia coli Putative acyl-CoA dehydrogenase AidB(aidB),Yeast
  • 货号：
    CSB-EP329241ENV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Escherichia coli Putative acyl-CoA dehydrogenase AidB(aidB),Yeast
  • 货号：
    CSB-EP329241ENV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Escherichia coli Putative acyl-CoA dehydrogenase AidB(aidB),Yeast
  • 货号：
    CSB-BP329241ENV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Escherichia coli Putative acyl-CoA dehydrogenase AidB(aidB),Yeast
  • 货号：
    CSB-MP329241ENV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    aidB
  • Uniprot No.：
  • 别名：
    aidB; b4187; JW5867Putative acyl-CoA dehydrogenase AidB; EC 1.3.99.-
  • 种属：
    Escherichia coli (strain K12)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-541
  • 氨基酸序列
    MHWQTHTVFN QPIPLNNSNL YLSDGALCEA VTREGAGWDS DFLASIGQQL GTAESLELGR LANVNPPELL RYDAQGRRLD DVRFHPAWHL LMQALCTNRV HNLAWEEDAR SGAFVARAAR FMLHAQVEAG SLCPITMTFA ATPLLLQMLP APFQDWTTPL LSDRYDSHLL PGGQKRGLLI GMGMTEKQGG SDVMSNTTRA ERLEDGSYRL VGHKWFFSVP QSDAHLVLAQ TAGGLSCFFV PRFLPDGQRN AIRLERLKDK LGNRSNASCE VEFQDAIGWL LGLEGEGIRL ILKMGGMTRF DCALGSHAMM RRAFSLAIYH AHQRHVFGNP LIQQPLMRHV LSRMALQLEG QTALLFRLAR AWDRRADAKE ALWARLFTPA AKFVICKRGM PFVAEAMEVL GGIGYCEESE LPRLYREMPV NSIWEGSGNI MCLDVLRVLN KQAGVYDLLS EAFVEVKGQD RYFDRAVRRL QQQLRKPAEE LGREITHQLF LLGCGAQMLK YASPPMAQAW CQVMLDTRGG VRLSEQIQND LLLRATGGVC V
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Part of the adaptive DNA-repair response to alkylating agents. Could prevent alkylation damage by protecting DNA and destroying alkylating agents that have yet to reach their DNA target. Binds to double-stranded DNA with a preference for a DNA region that includes its own promoter. Shows weak isovaleryl-CoA dehydrogenase activity in vitro.
  • 基因功能参考文献：
    1. AidB exhibits several discrepancies from ACADs that suggest a novel catalytic mechanism distinct from that of the ACAD family enzymes. PMID: 23443126
    2. AidB was found to bind to RNA, raising the prospect that the protein may have a role in protection of RNA from chemical alkylation. PMID: 21782785
    3. The N-terminal region, comprising the first 439 amino acids possesses dehydrogenase activity, while its C-terminal domain, corresponding to residues 440 to 541 displays DNA binding activity and can negatively regulate the expression of its own gene. PMID: 20889740
    4. AidB is shown to possess flavin adenine dinucleotide (FAD), low levels of isovaleryl-coenzyme A (CoA) dehydrogenase activity, and ability to bind DNA, and is predicted to catalyze the direct repair of alkylated DNA PMID: 16352838
    5. a 1.7-A crystal structure of AidB, which bears superficial resemblance to the acyl-CoA dehydrogenase superfamily of flavoproteins PMID: 18829440

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Acyl-CoA dehydrogenase family
  • 数据库链接：

    KEGG: ecj:JW5867

    STRING: 316385.ECDH10B_4382