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  4. Recombinant Human Beta-1,3-galactosyltransferase 5 (B3GALT5), partial

Recombinant Human Beta-1,3-galactosyltransferase 5 (B3GALT5), partial

  • 中文名称：
    Recombinant Human Beta-1,3-galactosyltransferase 5(B3GALT5),partial,Yeast
  • 货号：
    CSB-YP896690HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Beta-1,3-galactosyltransferase 5(B3GALT5),partial,Yeast
  • 货号：
    CSB-EP896690HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Beta-1,3-galactosyltransferase 5(B3GALT5),partial,Yeast
  • 货号：
    CSB-EP896690HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Beta-1,3-galactosyltransferase 5(B3GALT5),partial,Yeast
  • 货号：
    CSB-BP896690HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Beta-1,3-galactosyltransferase 5(B3GALT5),partial,Yeast
  • 货号：
    CSB-MP896690HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    B3GALT5
  • Uniprot No.：
  • 别名：
    3-galactosyltransferase 5; 3-GalTase 5; b3Gal-T5; B3GalT-V; B3GALT5; B3GalTx; B3GT5_HUMAN; B3T5; Beta-1; Beta-1,3-Gal Tase 5; Beta-1,3-galactosyltransferase 5; beta-1,3-GalTase 5; beta-3-galactosyltransferase 5; Beta-3-Gx-T5; Beta3Gal-T5; Beta3GalT5; GLCT5; Homolog of C. elegans Bt toxin resistance gene bre-5; UDP-Gal:beta-GlcNAc beta-1; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase; polypeptide 5; UDP-galactose:beta-N-acetylglucosamine beta-1; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor.
  • 基因功能参考文献：
    1. CA19.9 appears as a physiological product whose synthesis strongly depends on the tissue specific and epigenetically-regulated expression of B3GALT5 and ST3GAL3. PMID: 27535614
    2. Data conclude that HNF1alpha/beta are necessary but insufficient to activate and regulate B3GALT5 LTR transcription, which depends on unknown regulatory elements that are active when methylated and located outside of and far from the LTR promoter. PMID: 24128890
    3. Chromatin immunoprecipitation assays on beta3Gal-T5 promoter showed that histone H3K4 trymethylation, H3K79 dimethylation, and H3K9-14 acetylation are high in cells expressing the transcript. PMID: 22001559
    4. The B3GALT5 promoter is activated by serum depletion according to promoter reporter assays in HEK 293 cells. PMID: 20494980
    5. case study of the endogenous retrovirus long terminal repeat promoter of this enzyme PMID: 16112824
    6. the enhanced expression of beta 3GalT5 is sufficient to promote in vivo extension of type 1 chains by furnishing a significantly higher amount of type 1 chain precursors relative to competing type 2 chains. PMID: 19136585
    7. We found beta3Gal-T4 and T5 enzymatic activity in ovarian cancer tissues, indicating that these enzymes are expressed at least in ovarian cancer PMID: 19225246

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  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 31 family
  • 组织特异性：
    Expressed in stomach, jejunum, colon, pancreas, small intestine, testis and gastrointestinal and pancreatic cancer cell lines. Hardly detected in lung, liver, adrenal gland and peripheral blood leukocytes.
  • 数据库链接：

    HGNC: 920

    OMIM: 604066

    KEGG: hsa:10317

    STRING: 9606.ENSP00000343318

    UniGene: Hs.733638