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  4. Recombinant Human Beta-defensin 106 (DEFB106A)

Recombinant Human Beta-defensin 106 (DEFB106A)

  • 中文名称：
    Recombinant Human Beta-defensin 106(DEFB106A),Yeast
  • 货号：
    CSB-YP836640HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Beta-defensin 106(DEFB106A),Yeast
  • 货号：
    CSB-EP836640HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Beta-defensin 106(DEFB106A),Yeast
  • 货号：
    CSB-EP836640HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Beta-defensin 106(DEFB106A),Yeast
  • 货号：
    CSB-BP836640HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Beta-defensin 106(DEFB106A),Yeast
  • 货号：
    CSB-MP836640HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DEFB106A
  • Uniprot No.：
  • 别名：
    DEFB106A; BD6; DEFB106; DEFB6;; DEFB106BBeta-defensin 106; Beta-defensin 6; BD-6; DEFB-6; Defensin; beta 106
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    21-65
  • 氨基酸序列
    FFDEKCNKLK GTCKNNCGKN EELIALCQKS LKCCRTIQPC GSIID
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2.
  • 基因功能参考文献：
    1. Unique properties of human beta-defensin 6 (hBD6) and glycosaminoglycan complex: sandwich-like dimerization and competition with the chemokine receptor 2 (CCR2) binding site. PMID: 24970887
    2. DEFB106 (also known as DEFB6) displays antimicrobial activity against E. coli, C. albicans and S. aureus. PMID: 24189797
    3. The epididymis-specific expression pattern of the beta-defensin isoform BD-6 has been characterized. PMID: 12193721
    4. A pilot study with cRNA probes for in situ hybridization and a synthetic propeptide for the functional characterization demonstrated the tissue-/cell-specific expression and the strong antimicrobial activity of DEFB106 PMID: 12600824
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 19194307

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  • 亚细胞定位：
    Secreted. Membrane.
  • 蛋白家族：
    Beta-defensin family
  • 组织特异性：
    Expressed specifically in epididymis and lung.
  • 数据库链接：

    HGNC: 18088

    KEGG: hsa:245909

    STRING: 9606.ENSP00000335307

    UniGene: Hs.511958