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  4. Recombinant Human Endoplasmic reticulum resident protein 27 (ERP27)

Recombinant Human Endoplasmic reticulum resident protein 27 (ERP27)

  • 中文名称：
    人ERP27重组蛋白
  • 货号：
    CSB-YP842657HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人ERP27重组蛋白
  • 货号：
    CSB-EP842657HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人ERP27重组蛋白
  • 货号：
    CSB-EP842657HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人ERP27重组蛋白
  • 货号：
    CSB-BP842657HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人ERP27重组蛋白
  • 货号：
    CSB-MP842657HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ERP27
  • Uniprot No.：
  • 别名：
    C12orf46 ; Chromosome 12 open reading frame 46; Endoplasmic reticulum protein 27; Endoplasmic reticulum protein 27 kDa ; Endoplasmic reticulum resident protein 27; Endoplasmic reticulum resident protein ERp27; ER protein 27; ERp 27; ERp27; ERP27_HUMAN; FLJ32115; PDIA8; Protein disulfide isomerase family A; member 8
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    26-273
  • 氨基酸序列
    EVEKS SDGPGAAQEP TWLTDVPAAM EFIAATEVAV IGFFQDLEIP AVPILHSMVQ KFPGVSFGIS TDSEVLTHYN ITGNTICLFR LVDNEQLNLE DEDIESIDAT KLSRFIEINS LHMVTEYNPV TVIGLFNSVI QIHLLLIMNK ASPEYEENMH RYQKAAKLFQ GKILFILVDS GMKENGKVIS FFKLKESQLP ALAIYQTLDD EWDTLPTAEV SVEHVQNFCD GFLSGKLLKE NRESEGKTPK VEL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates. Binds protein substrates via a hydrophobic pocket in the C-terminal domain. May play a role in the unfolded stress response.
  • 基因功能参考文献：
    1. High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility PMID: 23234573
    2. ERp27 is able to distinguish between folded and unfolded substrates, only interacting with the latter and presenting them to for catalysis. PMID: 23192347
    3. ERp27 is bound by ERp57 both in vitro and in vivo by a similar mechanism by which ERp57 binds calreticulin PMID: 16940051
  • 亚细胞定位：
    Endoplasmic reticulum lumen.
  • 蛋白家族：
    Protein disulfide isomerase family
  • 数据库链接：

    HGNC: 26495

    OMIM: 610642

    KEGG: hsa:121506

    STRING: 9606.ENSP00000266397

    UniGene: Hs.162143