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  4. Recombinant Human GTP-binding protein 5 (GTPBP5)

Recombinant Human GTP-binding protein 5 (GTPBP5)

  • 中文名称：
    人MTG2重组蛋白
  • 货号：
    CSB-YP867150HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MTG2重组蛋白
  • 货号：
    CSB-EP867150HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MTG2重组蛋白
  • 货号：
    CSB-EP867150HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MTG2重组蛋白
  • 货号：
    CSB-BP867150HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MTG2重组蛋白
  • 货号：
    CSB-MP867150HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MTG2
  • Uniprot No.：
  • 别名：
    dJ1005F21.2; FLJ10741; GTP binding protein 5 (putative); GTP binding protein 5; GTP-binding protein 5; GTPB5_HUMAN; GTPBP5; Mitochondrial ribosome-associated GTPase 2; ObgH1; Protein obg homolog 1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-406
  • 氨基酸序列
    MAPARCFSAR LRTVFQGVGH WALSTWAGLK PSRLLPQRAS PRLLSVGRAD LAKHQELPGK KLLSEKKLKR YFVDYRRVLV CGGNGGAGAS CFHSEPRKEF GGPDGGDGGN GGHVILRVDQ QVKSLSSVLS RYQGFSGEDG GSKNCFGRSG AVLYIRVPVG TLVKEGGRVV ADLSCVGDEY IAALGGAGGK GNRFFLANNN RAPVTCTPGQ PGQQRVLHLE LKTVAHAGMV GFPNAGKSSL LRAISNARPA VASYPFTTLK PHVGIVHYEG HLQIAVADIP GIIRGAHQNR GLGSAFLRHI ERCRFLLFVV DLSQPEPWTQ VDDLKYELEM YEKGLSARPH AIVANKIDLP EAQANLSQLR DHLGQEVIVL SALTGENLEQ LLLHLKVLYD AYAEAELGQG RQPLRW
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays GTPase activity. Involved in the ribosome maturation process.
  • 基因功能参考文献：
    1. The results suggested that ObgH1 functions with the large subunit of the mitochondrial ribosome, and are involved in both the translation and assembly of respiratory complexes. PMID: 23396448
    2. GTPBP5 bears further study as a cause of TEF/EA accompanied by other malformations. PMID: 21608104
    3. Knock-down of ObgH1 by RNAi induced mitochondria elongation, whereas knock-down of ObgH2 resulted in the disorganization of the nucleolar architecture. PMID: 17054726
  • 亚细胞定位：
    Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family
  • 数据库链接：

    HGNC: 16239

    OMIM: 610919

    KEGG: hsa:26164

    STRING: 9606.ENSP00000359859

    UniGene: Hs.340636