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  4. Recombinant Human GTP-binding protein Di-Ras2 (DIRAS2)

Recombinant Human GTP-binding protein Di-Ras2 (DIRAS2)

  • 中文名称：
    人DIRAS2重组蛋白
  • 货号：
    CSB-YP856949HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人DIRAS2重组蛋白
  • 货号：
    CSB-EP856949HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人DIRAS2重组蛋白
  • 货号：
    CSB-EP856949HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人DIRAS2重组蛋白
  • 货号：
    CSB-BP856949HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人DIRAS2重组蛋白
  • 货号：
    CSB-MP856949HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DIRAS2
  • Uniprot No.：
  • 别名：
    DIRAS2GTP-binding protein Di-Ras2; Distinct subgroup of the Ras family member 2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-196
  • 氨基酸序列
    MPEQSNDYRV AVFGAGGVGK SSLVLRFVKG TFRESYIPTV EDTYRQVISC DKSICTLQIT DTTGSHQFPA MQRLSISKGH AFILVYSITS RQSLEELKPI YEQICEIKGD VESIPIMLVG NKCDESPSRE VQSSEAEALA RTWKCAFMET SAKLNHNVKE LFQELLNLEK RRTVSLQIDG KKSKQQKRKE KLKGKC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Displays low GTPase activity and exists predominantly in the GTP-bound form.
  • 基因功能参考文献：
    1. The results from the present study imply that rs1412005 in the DIRAS2 gene is in itself a causal variant, and that it is not only functional on the molecular, but also the inhibition-related brain activation level, the latter specifically in patients suffering from ADHD. PMID: 27364329
    2. Four single nucleotide polymorphisms (SNPs) and two haplotype blocks in DIRAS2 show evidence of association with attention deficit/hyperactivity disorder (ADHD) in adults. PMID: 21750579
  • 亚细胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Di-Ras family
  • 组织特异性：
    Highly expressed in brain.
  • 数据库链接：

    HGNC: 19323

    OMIM: 607863

    KEGG: hsa:54769

    STRING: 9606.ENSP00000364919

    UniGene: Hs.165636