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  4. Recombinant Human Nascent polypeptide-associated complex subunit alpha-2 (NACA2)

Recombinant Human Nascent polypeptide-associated complex subunit alpha-2 (NACA2)

  • 中文名称：
    人NACA2重组蛋白
  • 货号：
    CSB-YP887940HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NACA2重组蛋白
  • 货号：
    CSB-EP887940HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NACA2重组蛋白
  • 货号：
    CSB-EP887940HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NACA2重组蛋白
  • 货号：
    CSB-BP887940HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NACA2重组蛋白
  • 货号：
    CSB-MP887940HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NACA2
  • Uniprot No.：
  • 别名：
    NACA2; NACAL; Nascent polypeptide-associated complex subunit alpha-2; Alpha-NAC-like; Hom s 2.01; Nascent polypeptide-associated complex subunit alpha-like; NAC-alpha-like
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-215
  • 氨基酸序列
    MPGEATETVP ATEQELPQSQ AETGSGTASD SGESVPGIEE QDSTQTTTQK AWLVAAAEID EEPVGKAKQS RSEKRARKAM SKLGLLQVTG VTRVTIWKSK NILFVITKLD VYKSPASDAY IVFGEAKIQD LSQQAQLAAA EKFRVQGEAV GNIQENTQTP TVQEESEEEE VDETGVEVKD VKLVMSQANV SRAKAVRALK NNSNDIVNAI MELTV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).
  • 基因功能参考文献：
    1. Alpha-nac is a potent inducer of a Th1 response via IL12 and TLR2. PMID: 23657466
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 20546612
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    NAC-alpha family
  • 组织特异性：
    Expressed specifically in testis and skeletal muscle.
  • 数据库链接：

    HGNC: 23290

    OMIM: 609274

    KEGG: hsa:342538

    STRING: 9606.ENSP00000427802

    UniGene: Hs.591178