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  4. Recombinant Human Poly [ADP-ribose] polymerase 16 (PARP16), partial

Recombinant Human Poly [ADP-ribose] polymerase 16 (PARP16), partial

  • 中文名称：
    人PARP16重组蛋白
  • 货号：
    CSB-YP836673HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PARP16重组蛋白
  • 货号：
    CSB-EP836673HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PARP16重组蛋白
  • 货号：
    CSB-MP836673HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PARP16
  • Uniprot No.：
  • 别名：
    ADP ribosyltransferase diphtheria toxin like 15; ADP-ribosyltransferase diphtheria toxin-like 15; ARTD 15; ARTD15; C15orf30; Chromosome 15 open reading frame 30 ; EC 2.4.2.30 ; FLJ20509; FLJ25281; mono [ADP-ribose] polymerase PARP16; mono ADP ribose polymerase PARP16; PAR16_HUMAN; PARP 16; PARP-16; Parp16; pART 15; pART15; Poly (ADP ribose) polymerase family member 16; Poly [ADP ribose] polymerase 16; Poly [ADP-ribose] polymerase 16; poly ADP ribose polymerase 16
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Intracellular mono-ADP-ribosyltransferase that may play a role in different processes through the mono-ADP-ribosylation of proteins involved in those processes. May play a role in the unfolded protein response (UPR), by ADP-ribosylating and activating EIF2AK3 and ERN1, two important UPR effectors. May also mediate mono-ADP-ribosylation of karyopherin KPNB1 a nuclear import factor. May not modify proteins on arginine or cysteine residues compared to other mono-ADP-ribosyltransferases.
  • 基因功能参考文献：
    1. ARTD15 plays role in nucleocytoplasmic shuttling, through karyopherin-beta1 mono-ADP-ribosylation. [review] PMID: 25037261
    2. PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1alpha-mediated unfolded protein response. PMID: 23103912
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
  • 数据库链接：

    HGNC: 26040

    KEGG: hsa:54956

    STRING: 9606.ENSP00000261888

    UniGene: Hs.30634