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  4. Recombinant Human Retinoic acid early transcript 1L protein (RAET1L)

Recombinant Human Retinoic acid early transcript 1L protein (RAET1L)

  • 中文名称：
    人RAET1L重组蛋白
  • 货号：
    CSB-YP730141HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人RAET1L重组蛋白
  • 货号：
    CSB-EP730141HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人RAET1L重组蛋白
  • 货号：
    CSB-EP730141HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人RAET1L重组蛋白
  • 货号：
    CSB-BP730141HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人RAET1L重组蛋白
  • 货号：
    CSB-MP730141HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    RAET1L; ULBP6; UL16-binding protein 6; Retinoic acid early transcript 1L protein
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    26-218
  • 氨基酸序列
    RRDDP HSLCYDITVI PKFRPGPRWC AVQGQVDEKT FLHYDCGNKT VTPVSPLGKK LNVTMAWKAQ NPVLREVVDI LTEQLLDIQL ENYTPKEPLT LQARMSCEQK AEGHSSGSWQ FSIDGQTFLL FDSEKRMWTT VHPGARKMKE KWENDKDVAM SFHYISMGDC IGWLEDFLMG MDSTLEPSAG APLAMSSG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
  • 基因功能参考文献：
    1. ULBP6 polymorphisms affect the strength of human lymphocyte responses to cellular stress signals and is increased in abundance in hematopoietic tumors. PMID: 28559451
    2. RAET1L may have an important influence on regulating the strength of the alloreactive immune response in hematologic maliganacies treated with allogeneic stem cell transplantation. PMID: 23025544
    3. Here, we show that a sixth gene, ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript PMID: 19658097
  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum.
  • 蛋白家族：
    MHC class I family
  • 组织特异性：
    Widely expressed. Expressed in trachea. Constitutively expressed in peripheral blood mononuclear cells, including B-cells and natural killer cells, as well as CD4+ and CD8+ T-cells and monocytes. Tends to be up-regulated in various lymphoid malignancies,
  • 数据库链接：

    HGNC: 16798

    OMIM: 611047

    KEGG: hsa:154064

    STRING: 9606.ENSP00000286380

    UniGene: Hs.558659