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  4. Recombinant Human Solute carrier family 13 member 4 (SLC13A4), partial

Recombinant Human Solute carrier family 13 member 4 (SLC13A4), partial

  • 中文名称：
    人SLC13A4重组蛋白
  • 货号：
    CSB-YP891949HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SLC13A4重组蛋白
  • 货号：
    CSB-EP891949HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SLC13A4重组蛋白
  • 货号：
    CSB-EP891949HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SLC13A4重组蛋白
  • 货号：
    CSB-BP891949HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SLC13A4重组蛋白
  • 货号：
    CSB-MP891949HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC13A4
  • Uniprot No.：
  • 别名：
    Na(+)/sulfate cotransporter SUT-1; NaS2; S13A4_HUMAN; SLC13A4; Solute carrier family 13 member 4; SUT1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV).
  • 基因功能参考文献：
    1. Study found that despite differential expression of the two SLC13A4 transcripts, no detectable functional difference in the cellular sorting or sulfate transporting was found. However, some variants can influence both mechanism in specific cell membranes. This is like to have clinical implications based on the consequences of impaired sulfate transport during pregnancy in rodent models. PMID: 28385533
    2. SLC13A4 and SLC26A2 were the most abundant sulfate transporter mRNAs, which localized to syncytiotrophoblast and cytotrophoblast cells, respectively. PMID: 23453247
    3. To investigate the regulation of SLC13A4 gene expression, we analysed the transcriptional activity of the SLC13A4 5'-flanking region in the JEG-3 placental cell line using luciferase reporter assays. PMID: 23485456
    4. Here, we characterized the functional properties of the human Na(+)-sulfate cotransporter (hNaS2), determined its tissue distribution, and identified its gene (SLC13A4) structure. PMID: 15607730
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SLC13A/DASS transporter (TC 2.A.47) family, NADC subfamily
  • 组织特异性：
    Highly expressed in placenta and testis with intermediate levels in brain and lower levels in heart, thymus and liver.
  • 数据库链接：

    HGNC: 15827

    OMIM: 604309

    KEGG: hsa:26266

    STRING: 9606.ENSP00000297282

    UniGene: Hs.490241