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  4. Recombinant Human Solute carrier family 17 member 9 (SLC17A9), partial

Recombinant Human Solute carrier family 17 member 9 (SLC17A9), partial

  • 中文名称：
    人SLC17A9重组蛋白
  • 货号：
    CSB-YP880141HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SLC17A9重组蛋白
  • 货号：
    CSB-EP880141HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SLC17A9重组蛋白
  • 货号：
    CSB-EP880141HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SLC17A9重组蛋白
  • 货号：
    CSB-BP880141HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SLC17A9重组蛋白
  • 货号：
    CSB-MP880141HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC17A9
  • Uniprot No.：
  • 别名：
    C20orf59; S17A9_HUMAN; Slc17a9; Solute carrier family 17 (vesicular nucleotide transporter) member 9; Solute carrier family 17 member 9; VNUT
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles.
  • 基因功能参考文献：
    1. Results identified SLC17A9 as another pathogenic gene for DSAP, which suggests a correlation between the aberrant vesicular nucleotide transporter and the pathogenesis of DSAP. PMID: 25180256
    2. data suggest that SLC17A9 activity mediates lysosomal ATP accumulation and plays an important role in lysosomal physiology and cell viability. PMID: 24962569
    3. It is suggested that the functions of VNUT, in addition to P2 receptors may be a target for anti-inflammatory response in skin. PMID: 24292772
    4. These results suggest that SLC17A9 is the relevant nucleotide transporter responsible for the uptake of cytosolic nucleotides into mucin granules. PMID: 23467297
    5. the existence of an SLC17A9-dependent ATP-enriched vesicular pool in biliary epithelium that undergoes regulated exocytosis to initiate purinergic signaling. PMID: 21613220
    6. analysis of involvement of SLC17A9-dependent vesicular exocytosis in the mechanism of ATP release during T cell activation PMID: 20382737
    7. SLC17A9 protein acts as a vesicular nucleotide transporter (VNUT) and plays an essential role in vesicular storage of ATP in the ATP-secreting cells [SLC17A9] PMID: 18375752

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  • 相关疾病：
    Porokeratosis 8, disseminated superficial actinic type (POROK8)
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Major facilitator superfamily, Sodium/anion cotransporter family
  • 组织特异性：
    Predominantly expressed in adrenal gland, brain and thyroid.
  • 数据库链接：

    HGNC: 16192

    OMIM: 612107

    KEGG: hsa:63910

    STRING: 9606.ENSP00000359376

    UniGene: Hs.512686