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  4. Recombinant Human Sorting nexin-8 (SNX8)

Recombinant Human Sorting nexin-8 (SNX8)

  • 中文名称：
    人SNX8重组蛋白
  • 货号：
    CSB-YP896744HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SNX8重组蛋白
  • 货号：
    CSB-EP896744HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SNX8重组蛋白
  • 货号：
    CSB-EP896744HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SNX8重组蛋白
  • 货号：
    CSB-BP896744HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SNX8重组蛋白
  • 货号：
    CSB-MP896744HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SNX8
  • Uniprot No.：
  • 别名：
    DKFZp761E1721; Highly similar to MVP1 PROTEIN Saccharomyces cerevisiae; Mvp1; OTTHUMP00000200137; SNX 8; SNX8; SNX8_HUMAN; Sorting nexin 8; Sorting nexin-8
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-465
  • 氨基酸序列
    MTGRAMDPLP AAAVGAAAEA EADEEADPPA SDLPTPQAIE PQAIVQQVPA PSRMQMPQGN PLLLSHTLQE LLARDTVQVE LIPEKKGLFL KHVEYEVSSQ RFKSSVYRRY NDFVVFQEML LHKFPYRMVP ALPPKRMLGA DREFIEARRR ALKRFVNLVA RHPLFSEDVV LKLFLSFSGS DVQNKLKESA QCVGDEFLNC KLATRAKDFL PADIQAQFAI SRELIRNIYN SFHKLRDRAE RIASRAIDNA ADLLIFGKEL SAIGSDTTPL PSWAALNSST WGSLKQALKG LSVEFALLAD KAAQQGKQEE NDVVEKLNLF LDLLQSYKDL CERHEKGVLH KHQRALHKYS LMKRQMMSAT AQNREPESVE QLESRIVEQE NAIQTMELRN YFSLYCLHQE TQLIHVYLPL TSHILRAFVN SQIQGHKEMS KVWNDLRPKL SCLFAGPHST LTPPCSPPED GLCPH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network.
  • 基因功能参考文献：
    1. SNX8 mediates IFNG-triggered non-canonical signaling pathway and host defense against Listeria monocytogenes. PMID: 29180417
    2. SNX8: A candidate gene for 7p22 cardiac malformations including tetralogy of fallot. PMID: 24311514
    3. SNX4, but not SNX1 and SNX8, is associated with the Rab11-recycling endosomes and that a high frequency of SNX4-mediated tubule formation is observed as endosomes undergo Rab4-to-Rab11 transition. PMID: 21973056
  • 亚细胞定位：
    Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with retromer components.
  • 蛋白家族：
    Sorting nexin family
  • 数据库链接：

    HGNC: 14972

    OMIM: 614905

    KEGG: hsa:29886

    STRING: 9606.ENSP00000222990

    UniGene: Hs.584900