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  4. Recombinant Human Spermatid-specific manchette-related protein 1 (SMRP1)

Recombinant Human Spermatid-specific manchette-related protein 1 (SMRP1)

  • 中文名称：
    人SMRP1重组蛋白
  • 货号：
    CSB-YP847685HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SMRP1重组蛋白
  • 货号：
    CSB-EP847685HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SMRP1重组蛋白
  • 货号：
    CSB-EP847685HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SMRP1重组蛋白
  • 货号：
    CSB-BP847685HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SMRP1重组蛋白
  • 货号：
    CSB-MP847685HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SMRP1
  • Uniprot No.：
  • 别名：
    SMRP1; C9orf24; CBE1Spermatid-specific manchette-related protein 1; Ciliated bronchial epithelial protein 1; Testis development protein NYD-SP22
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-262
  • 氨基酸序列
    MFLFSRKTRT PISTYSDSYR APTSIKEVYK DPPLCAWEAN KFLTPGLTHT MERHVDPEAL QKMAKCAVQD YTYRGSISGH PYLPEKYWLS QEEADKCSPN YLGSDWYNTW RMEPYNSSCC NKYTTYLPRL PKEARMETAV RGMPLECPPR PERLNAYERE VMVNMLNSLS RNQQLPRITP RCGCVDPLPG RLPFHGYESA CSGRHYCLRG MDYYASGAPC TDRRLRPWCR EQPTMCTSLR APARNAVCCY NSPAVILPIS EP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in spermatogenesis. May be involved in differentiation or function of ciliated cells.
  • 基因功能参考文献：
    1. Our data strongly suggest an influence of CBE1 in ciliogenesis in spermatids due to the localization at the microtubules of the elongating spermatids, indicating a role in the intramanchette and/or intraflagellar transport mechanism. PMID: 28601408
    2. CBE1 may play an important role in the differentiation and/or function of ciliated cells in human airways PMID: 15242845
    3. Chronological regulation of CBE1/Cbe1 expression during pulmonary differentiation suggests involvement in ciliogenesis, with an additional role during early lung development. PMID: 19213785
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Nucleus. Cytoplasm.
  • 蛋白家族：
    SMRP1 family
  • 组织特异性：
    Expressed in epithelial cells of nasal polyps and in intact epithelium of bronchial biopsies from subjects with and without asthma. Strong expression in columnar cells with little or no expression in basal epithelial cells along the basement membrane. Str
  • 数据库链接：

    HGNC: 19919

    KEGG: hsa:84688

    STRING: 9606.ENSP00000297623

    UniGene: Hs.50334