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  4. Recombinant Human Synaptotagmin-like protein 5 (SYTL5)

Recombinant Human Synaptotagmin-like protein 5 (SYTL5)

  • 中文名称：
    人SYTL5重组蛋白
  • 货号：
    CSB-YP855060HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SYTL5重组蛋白
  • 货号：
    CSB-EP855060HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SYTL5重组蛋白
  • 货号：
    CSB-EP855060HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SYTL5重组蛋白
  • 货号：
    CSB-BP855060HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SYTL5重组蛋白
  • 货号：
    CSB-MP855060HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SYTL5
  • Uniprot No.：
  • 别名：
    SLP5; Synaptotagmin-like 5; Synaptotagmin-like protein 5; Sytl5; SYTL5_HUMAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-730
  • 氨基酸序列
    MSKNSEFINL SFLLDHEKEM ILGVLKRDEY LKKVEDKRIR KLKNELLEAK RRSGKTQQEA SRVCVHCHRN LGLIFDRGDP CQACSLRVCR ECRVAGPNGS WKCTVCDKIA QLRIITGEWF FEEKAKRFKQ VNVLGTDVVR QSILRRSPGA EEVQSQEQTR QDAEKSDTSP VAGKKASHDG PKRKGFLLSK FRSATRGEII TPKTDTGRSY SLDLDGQHFR SLKSPPGSDR GSTGSSDLND QEPGPRTPKS SRSNGVTPGT QSSPAPSTRT VTSVISREYG FENSMDLAAI EGTSQELTKS HRRNTSGTPS IAVSGTSLSS DQSRSELDLS ESFTEDSEDT VSIRSKSVPG ALDKDSLEET EESIDALVSS QLSTNTHRLA SGLSTTSLNS MMSVYSETGD YGNVKVSGEI LLHISYCYKT GGLYIFVKNC RNLAIGDEKK QRTDAYVKSY LLPDKSRNNK RKTKIRTGTN PEFNETLKYT ISHTQLETRT LQLSVWHYDR FGRNSFLGEV EIPFDSWNFE NPTDEWFVLQ PKVEFAPDIG LQYKGELTVV LRYIPPEENL MLPPEQLQGN KTFKKGKKKE SPVISGGILE VFIKEAKNLT AVKSGGTSDS FVKGYLLPDD SKATKHKTLV IKKSVNPQWN HTFMFSGIHP QDIKNVCLEL TIWDKEAFSS NIFLGGVRLN SGSGVSHGKN VDWMDSQGEE QRLWQKMANN PGTPFEGVLM LRSSMGKCRL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids.
  • 基因功能参考文献：
    1. molecular cloning of slp5:a novel Rab27A effector with C-terminal tandem C2 domains PMID: 12051743
    2. These observations decisively prove that Rab27a inhibits ENaC function through a complex mechanism that involves GTP/GDP status, and protein-protein interactions involving Munc13-4 and SLP-5 effector proteins. PMID: 16630545
    3. Synaptotagmin-like protein 5 (Slp5) contains an N-terminal Slp homology domain (SHD) (PMID: 11327731). The SHD of Slp5 specifically and directly binds the GTP-bound form of Rab27A. PMID: 12051743
  • 亚细胞定位：
    Membrane; Peripheral membrane protein.
  • 组织特异性：
    Highly expressed in placenta and liver.
  • 数据库链接：

    HGNC: 15589

    KEGG: hsa:94122

    STRING: 9606.ENSP00000395220

    UniGene: Hs.662334