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  4. Recombinant Human Testis-expressed sequence 101 protein (TEX101)

Recombinant Human Testis-expressed sequence 101 protein (TEX101)

  • 中文名称：
    人TEX101重组蛋白
  • 货号：
    CSB-YP887155HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人TEX101重组蛋白
  • 货号：
    CSB-EP887155HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人TEX101重组蛋白
  • 货号：
    CSB-EP887155HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人TEX101重组蛋白
  • 货号：
    CSB-BP887155HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人TEX101重组蛋白
  • 货号：
    CSB-MP887155HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TEX101
  • Uniprot No.：
  • 别名：
    TEX101; SGRG; UNQ867/PRO1884; Testis-expressed protein 101; Cell surface receptor NYD-SP8; Scleroderma-associated autoantigen; Spermatogenesis-related gene protein
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    26-222
  • 氨基酸序列
    LYCQK GLSMTVEADP ANMFNWTTEE VETCDKGALC QETILIIKAG TETAILATKG CIPEGEEAIT IVQHSSPPGL IVTSYSNYCE DSFCNDKDSL SQFWEFSETT ASTVSTTLHC PTCVALGTCF SAPSLPCPNG TTRCYQGKLE ITGGGIESSV EVKGCTAMIG CRLMSGILAV GPMFVREACP HQLLTQPRKT EN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct. May play a role in signal transduction and promote protein tyrosine phosphorylation.
  • 基因功能参考文献：
    1. Overexpression of TEX101 is associated with breast tumors. PMID: 25994570
    2. Clinical assays for ECM1 and TEX101 have the potential to replace most of the diagnostic testicular biopsies and facilitate the prediction of outcome of sperm retrieval procedures, increasing the reliability and success of assisted reproduction techniques PMID: 24259048
    3. TEX101 is a cancer-testis (CT) gene useful for detection of CML. It was expressed in 30% of CML patients, but not in healthy donors. Unlike many CT genes, overexpression of TEX101 was not shown to induce immunologic responses in these samples. PMID: 22588436
    4. Combination of two proteins, SPAG11B and TEX101, can be used for differential diagnosis of azoospermia PMID: 21933954
    5. Overexpression of NYD-SP8 in various nasopharyngeal carcinoma cell lines indicated its complicated functions, and that it could play an important role in nasopharyngeal carcinoma carcinogenesis. PMID: 22158499
    6. NYD-SP8 has a role in regulating ECM degradation, providing a novel mechanism that modulates urokinase signalling in the suppression of cancer progression PMID: 19017363
    7. The SPATA19 and TEX101 genes may be possible targets for cancer immunotherapy and novel markers for early detection of basal cell carcinoma. PMID: 19886887
    8. identification & function of a novel sperm GPI-anchored membrane protein, NYD-SP8; release of NYD-SP8 during sperm-egg interaction & binding to cumulus elicits cross-talk between the gametes leading to the acrosome reaction PMID: 19153666

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  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Cytoplasmic vesicle, secretory vesicle, acrosome. Secreted. Cytoplasmic vesicle.
  • 组织特异性：
    Detected in testis and spermatogonia. Not detected in spermatocytes. Detected in blood leukocytes.
  • 数据库链接：

    HGNC: 30722

    OMIM: 612665

    KEGG: hsa:83639

    STRING: 9606.ENSP00000253435

    UniGene: Hs.97978