Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Human Transcription factor HES-7 (HES7)

Recombinant Human Transcription factor HES-7 (HES7)

  • 中文名称：
    人HES7重组蛋白
  • 货号：
    CSB-YP887160HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人HES7重组蛋白
  • 货号：
    CSB-EP887160HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人HES7重组蛋白
  • 货号：
    CSB-EP887160HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人HES7重组蛋白
  • 货号：
    CSB-BP887160HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人HES7重组蛋白
  • 货号：
    CSB-MP887160HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    HES7
  • Uniprot No.：
  • 别名：
    bHLH factor Hes7; bHLHb37; Class B basic helix loop helix protein 37; Class B basic helix-loop-helix protein 37; Hairy and enhancer of split 7; hes family bHLH transcription factor 7; Hes7; HES7_HUMAN; hHes7; SCDO4; Transcription factor HES 7; Transcription factor HES-7
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-225
  • 氨基酸序列
    MVTRDRAENR DGPKMLKPLV EKRRRDRINR SLEELRLLLL ERTRDQNLRN PKLEKAEILE FAVGYLRERS RVEPPGVPRS PVQDAEALAS CYLSGFRECL LRLAAFAHDA SPAARAQLFS ALHGYLRPKP PRPKPVDPRP PAPRPSLDPA APALGPALHQ RPPVHQGHPS PRCAWSPSLC SPRAGDSGAP APLTGLLPPP PPPHRQDGAP KAPLPPPPAF WRPWP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation.
  • 基因功能参考文献：
    1. mutation of HES7 is uniquely associated with defects in vertebral, heart and neural tube formation, and this observation will help provide a discriminatory diagnostic guide in patients with SCD, as well as inform molecular genetic testing. PMID: 23897666
    2. MESP2, HES7 and DUSP6 genes may not be involved in the etiopathogenesis of sporadic and non-syndromic CS in Chinese Han population. PMID: 22744456
    3. Two new missense mutations in HES7 in a family with spondylocostal dysostosis. PMID: 20087400
    4. R25W missense mutation of HES7 is causative of Spondylocostal dysostosis. PMID: 18775957
  • 相关疾病：
    Spondylocostal dysostosis 4, autosomal recessive (SCDO4)
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 15977

    OMIM: 608059

    KEGG: hsa:84667

    STRING: 9606.ENSP00000446205

    UniGene: Hs.434828