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  4. Recombinant Human Transmembrane protein 150B (TMEM150B), partial

Recombinant Human Transmembrane protein 150B (TMEM150B), partial

  • 中文名称：
    人TMEM150B重组蛋白
  • 货号：
    CSB-YP405636HU1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人TMEM150B重组蛋白
  • 货号：
    CSB-EP405636HU1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人TMEM150B重组蛋白
  • 货号：
    CSB-EP405636HU1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人TMEM150B重组蛋白
  • 货号：
    CSB-BP405636HU1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人TMEM150B重组蛋白
  • 货号：
    CSB-MP405636HU1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TMEM150B
  • Uniprot No.：
  • 别名：
    TMEM150B; TMEM224; Modulator of macroautophagy TMEM150B; Protein DRAM-3; Transmembrane protein 150B; Transmembrane protein 224
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux. Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner. May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival.
  • 基因功能参考文献：
    1. TMEM150B expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    2. TMEM150B, renamed as DRAM-3, is a modulator of both macroautophagy and cell survival under starvation conditions. PMID: 25929859
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein.
  • 蛋白家族：
    DRAM/TMEM150 family
  • 组织特异性：
    Highly expressed in the colon and lung with comparatively high levels also detectable in the lymph nodes, placenta, duodenum, peripheral blood mononuclear cells and spleen.
  • 数据库链接：

    HGNC: 34415

    KEGG: hsa:284417

    STRING: 9606.ENSP00000320757

    UniGene: Hs.382625