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  4. Recombinant Human U11/U12 small nuclear ribonucleoprotein 48 kDa protein (SNRNP48)

Recombinant Human U11/U12 small nuclear ribonucleoprotein 48 kDa protein (SNRNP48)

  • 中文名称：
    人SNRNP48重组蛋白
  • 货号：
    CSB-YP750321HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SNRNP48重组蛋白
  • 货号：
    CSB-EP750321HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SNRNP48重组蛋白
  • 货号：
    CSB-EP750321HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SNRNP48重组蛋白
  • 货号：
    CSB-BP750321HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SNRNP48重组蛋白
  • 货号：
    CSB-MP750321HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SNRNP48
  • Uniprot No.：
  • 别名：
    SNRNP48; C6orf151; U11/U12 small nuclear ribonucleoprotein 48 kDa protein; U11/U12 snRNP 48 kDa protein; U11/U12-48K
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-339
  • 氨基酸序列
    MEGEPPPVEE RRRLQEELNE FVESGCRTLE EVTASLGWDL DSLDPGEEEA AEDEVVICPY DSNHHMPKSS LAKHMASCRL RKMGYTKEEE DEMYNPEFFY ENVKIPSITL NKDSQFQIIK QARTAVGKDS DCYNQRIYSS LPVEVPLNHK RFVCDLTQAD RLALYDFVVE ETKKKRSDSQ IIENDSDLFV DLAAKINQDN SRKSPKSYLE ILAEVRDYKR RRQSYRAKNV HITKKSYTEV IRDVINVHME ELSNHWQEEQ EKAEDDAEKN EERRSASVDS RQSGGSYLDA ECSRHRRDRS RSPHKRKRNK DKDKNCESRR RKERDGERHH SHKRRKQKI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Likely involved in U12-type 5' splice site recognition.
  • 基因功能参考文献：
    1. RNA interference-induced knockdown of 48K led to reduced cell growth and the inhibition of U12-type splicing, as well as the activation of cryptic, U2-type splice sites, suggesting that 48K plays a critical role in U12-type intron recognition. PMID: 18347052
    2. A model in which the U11-48K Zn finger stabilizes U11-5' splice site base pairing and thus plays an important role during the minor spliceosome assembly. PMID: 19217400
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 21368

    KEGG: hsa:154007

    STRING: 9606.ENSP00000339834

    UniGene: Hs.13366