Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Human UBX domain-containing protein 4 (UBXN4)

Recombinant Human UBX domain-containing protein 4 (UBXN4)

  • 中文名称：
    人UBXN4重组蛋白
  • 货号：
    CSB-YP842131HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人UBXN4重组蛋白
  • 货号：
    CSB-EP842131HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人UBXN4重组蛋白
  • 货号：
    CSB-EP842131HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人UBXN4重组蛋白
  • 货号：
    CSB-BP842131HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人UBXN4重组蛋白
  • 货号：
    CSB-MP842131HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    UBXN4
  • Uniprot No.：
  • 别名：
    UBXN4; KIAA0242; UBXD2; UBXDC1; UBX domain-containing protein 4; Erasin; UBX domain-containing protein 2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-508
  • 氨基酸序列
    MLWFQGAIPA AIATAKRSGA VFVVFVAGDD EQSTQMAASW EDDKVTEASS NSFVAIKIDT KSEACLQFSQ IYPVVCVPSS FFIGDSGIPL EVIAGSVSAD ELVTRIHKVR QMHLLKSETS VANGSQSESS VSTPSASFEP NNTCENSQSR NAELCEIPPT SDTKSDTATG GESAGHATSS QEPSGCSDQR PAEDLNIRVE RLTKKLEERR EEKRKEEEQR EIKKEIERRK TGKEMLDYKR KQEEELTKRM LEERNREKAE DRAARERIKQ QIALDRAERA ARFAKTKEEV EAAKAAALLA KQAEMEVKRE SYARERSTVA RIQFRLPDGS SFTNQFPSDA PLEEARQFAA QTVGNTYGNF SLATMFPRRE FTKEDYKKKL LDLELAPSAS VVLLPAGRPT ASIVHSSSGD IWTLLGTVLY PFLAIWRLIS NFLFSNPPPT QTSVRVTSSE PPNPASSSKS EKREPVRKRV LEKRGDDFKK EGKIYRLRTQ DDGEDENNTW NGNSTQQM
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.
  • 基因功能参考文献：
    1. Erasin/UBXD2 may be involved in endoplasmic-reticulum-associated protein degradation and in Alzheimer's disease. PMID: 16968747
    2. Knockdown of erasin, a platform for p97/VCP and ubiquilin binding, or knockdown of ubiquilin in human cells slowed degradation of two classical endoplasmic reticulum-associated protein degradation substrates. PMID: 19822669
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope.
  • 组织特异性：
    Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level).
  • 数据库链接：

    HGNC: 14860

    OMIM: 611216

    KEGG: hsa:23190

    STRING: 9606.ENSP00000272638

    UniGene: Hs.591242