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  4. Recombinant Human UDP-glucuronic acid decarboxylase 1 (UXS1), partial

Recombinant Human UDP-glucuronic acid decarboxylase 1 (UXS1), partial

  • 中文名称：
    人UXS1重组蛋白
  • 货号：
    CSB-YP822754HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人UXS1重组蛋白
  • 货号：
    CSB-EP822754HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人UXS1重组蛋白
  • 货号：
    CSB-EP822754HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人UXS1重组蛋白
  • 货号：
    CSB-BP822754HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人UXS1重组蛋白
  • 货号：
    CSB-MP822754HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    UXS1
  • Uniprot No.：
  • 别名：
    UXS1; UNQ2538/PRO6079; UDP-glucuronic acid decarboxylase 1; EC 4.1.1.35; UDP-glucuronate decarboxylase 1; UGD; UXS-1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
  • 基因功能参考文献：
    1. The persistence of a latent hexamer-building interface in the human enzyme suggests that the ancestral UXS may have been a hexamer. PMID: 25521717
    2. hUXS forms a tetramer in solution that is important for activity. The higher activity of the tetramer coupled with the relative instability of the dimeric complex suggests that an association-dissociation mechanism may regulate hUXS activity. PMID: 23656592
    3. UDP-glucuronate decarboxylase, a key enzyme in proteoglycan synthesis: cloning, characterization, and localization. PMID: 11877387
    4. Complementation was achieved by expression of a cytoplasmic variant of UDP-xylose Synthase, which proves the existence of a functional Golgi UDP-xylose transporter[UDP-xylose Synthase] PMID: 19028698
  • 亚细胞定位：
    Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    NAD(P)-dependent epimerase/dehydratase family, UDP-glucuronic acid decarboxylase subfamily
  • 数据库链接：

    HGNC: 17729

    OMIM: 609749

    KEGG: hsa:80146

    STRING: 9606.ENSP00000387019

    UniGene: Hs.469561