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  4. Recombinant Human Uncharacterized protein C1orf135 (C1orf135)

Recombinant Human Uncharacterized protein C1orf135 (C1orf135)

  • 中文名称：
    Recombinant Human Uncharacterized protein C1orf135(C1orf135),Yeast
  • 货号：
    CSB-YP867168HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Uncharacterized protein C1orf135(C1orf135),Yeast
  • 货号：
    CSB-EP867168HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Uncharacterized protein C1orf135(C1orf135),Yeast
  • 货号：
    CSB-EP867168HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Uncharacterized protein C1orf135(C1orf135),Yeast
  • 货号：
    CSB-BP867168HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Uncharacterized protein C1orf135(C1orf135),Yeast
  • 货号：
    CSB-MP867168HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    AUNIP
  • Uniprot No.：
  • 别名：
    C1orf135; CA135_HUMAN; Uncharacterized protein C1orf135
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-357
  • 氨基酸序列
    MRRTGPEEEA CGVWLDAAAL KRRKVQTHLI KPGTKMLTLL PGERKANIYF TQRRAPSTGI HQRSIASFFT LQPGKTNGSD QKSVSSHTES QINKESKKNA TQLDHLIPGL AHDCMASPLA TSTTADIQEA GLSPQSLQTS GHHRMKTPFS TELSLLQPDT PDCAGDSHTP LAFSFTEDLE SSCLLDRKEE KGDSARKWEW LHESKKNYQS MEKHTKLPGD KCCQPLGKTK LERKVSAKEN RQAPVLLQTY RESWNGENIE SVKQSRSPVS VFSWDNEKND KDSWSQLFTE DSQGQRVIAH NTRAPFQDVT NNWNWDLGPF PNSPWAQCQE DGPTQNLKPD LLFTQDSEGN QVIRHQF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    DNA-binding protein that accumulates at DNA double-strand breaks (DSBs) following DNA damage and promotes DNA resection and homologous recombination. Serves as a sensor of DNA damage: binds DNA with a strong preference for DNA substrates that mimic structures generated at stalled replication forks, and anchors RBBP8/CtIP to DSB sites to promote DNA end resection and ensuing homologous recombination repair. Inhibits non-homologous end joining (NHEJ). Required for the dynamic movement of AURKA at the centrosomes and spindle apparatus during the cell cycle.
  • 基因功能参考文献：
    1. AIBp may not only be required for the dynamic movement of Aurora-A at the centrosomes and spindle apparatus during the cell cycle, but may also be important during brain tumorigenesis. PMID: 20596670
  • 亚细胞定位：
    Nucleus. Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族：
    AUNIP family
  • 组织特异性：
    Expressed in heart, skeletal muscles, placenta and testis.
  • 数据库链接：

    HGNC: 28363

    KEGG: hsa:79000

    STRING: 9606.ENSP00000363416

    UniGene: Hs.149305