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  4. Recombinant Human Uronyl 2-sulfotransferase (UST), partial

Recombinant Human Uronyl 2-sulfotransferase (UST), partial

  • 中文名称：
    人UST重组蛋白
  • 货号：
    CSB-YP897525HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人UST重组蛋白
  • 货号：
    CSB-EP897525HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人UST重组蛋白
  • 货号：
    CSB-EP897525HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人UST重组蛋白
  • 货号：
    CSB-BP897525HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人UST重组蛋白
  • 货号：
    CSB-MP897525HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    UST
  • Uniprot No.：
  • 别名：
    2OST; DS2ST; Uronyl 2-sulfotransferase; uronyl-2-sulfotransferase; Ust; UST_HUMAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin.
  • 基因功能参考文献：
    1. Results show that overexpression of 2OST alone in the HEK293 cells did not appreciably affect heparan sulfate (HS) chain length. Also, its simultaneous overexpression with Hsepi abolished the effect of Hsepi overexpression on the HS chain lengh. PMID: 27511124
    2. Statistical analysis showed the strongest evidence for a variant located in an intron of UST associated with job-related exhaustion. PMID: 23620144
    3. 2OST transfers sulfate preferentially to the GlcA residue located in a unique sequence, -GalNAc(4SO(4))-GlcA-GalNAc(6SO(4))-. PMID: 16192264
    4. analysis of differences and similarities various residues play in the biological roles of the HS-2OST and CS-2OST enzymes PMID: 17227754
  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Sulfotransferase 3 family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 17223

    OMIM: 610752

    KEGG: hsa:10090

    STRING: 9606.ENSP00000356433

    UniGene: Hs.657370