Recombinant Human cAMP-regulated phosphoprotein 19 (ARPP19)
-
货号:CSB-YP348885HU
-
规格:
-
来源:Yeast
-
其他:
-
货号:CSB-EP348885HU
-
规格:
-
来源:E.coli
-
其他:
-
货号:CSB-EP348885HU-B
-
规格:
-
来源:E.coli
-
共轭:Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
-
其他:
-
货号:CSB-BP348885HU
-
规格:
-
来源:Baculovirus
-
其他:
-
货号:CSB-MP348885HU
-
规格:
-
来源:Mammalian cell
-
其他:
产品详情
-
纯度:>85% (SDS-PAGE)
-
基因名:ARPP19
-
Uniprot No.:
-
别名:ARP19; ARP19_HUMAN; ARPP-19; Arpp19; cAMP-regulated phosphoprotein 19
-
种属:Homo sapiens (Human)
-
蛋白长度:Full Length of Mature Protein
-
表达区域:2-112
-
氨基酸序列SAEVPEAAS AEEQKEMEDK VTSPEKAEEA KLKARYPHLG QKPGGSDFLR KRLQKGQKYF DSGDYNMAKA KMKNKQLPTA APDKTEVTGD HIPTPQDLPQ RKPSLVASKL AG
-
蛋白标签:Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
产品提供形式:Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
复溶:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
-
储存条件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
-
保质期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
货期:Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
-
注意事项:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
Datasheet :Please contact us to get it.
相关产品
靶点详情
-
功能:Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.
-
基因功能参考文献:
- Together, the results suggest a complex antagonistic interplay between the control of ARPP-16 by MAST3 and PKA that creates a mechanism whereby cAMP mediates PP2A disinhibition. PMID: 28613156
- Study showed that ARPP-19 promoted both proliferation and metastasis of human glioma cells and the expression of ARPP-19 and CD147 in high-grade glioma was significantly higher than that in the low-grade glioma. PMID: 27380244
- Data show that micrRNA miR-320a directly targets cAMP-regulated phosphoprotein 19 (ARPP-19) and estrogen-related receptor gamma protein (ERRgamma) in breast cancer cell lines. PMID: 25736597
- ARPP-19 may play a role in HCC pathogenesis through regulating cell proliferation. PMID: 25547487
- ARPP19 gene expression is decreased in follicular variant of papillary thyroid carcinoma. PMID: 21509594
- Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease. PMID: 11771749
显示更多
收起更多
-
亚细胞定位:Cytoplasm.
-
蛋白家族:Endosulfine family
-
数据库链接:
HGNC: 16967
OMIM: 605487
KEGG: hsa:10776
STRING: 9606.ENSP00000249822
UniGene: Hs.512908
Most popular with customers
-
Recombinant Human Transthyretin (TTR) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Delta-like protein 3 (DLL3), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Neuropilin-1 (NRP1) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Glucagon receptor (GCGR), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Complement component C1q receptor (CD93), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Mucin-17 (MUC17), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 8(CEACAM8) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Urokinase-type plasminogen activator(PLAU) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)