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  4. Recombinant Mouse Abhydrolase domain-containing protein 4 (Abhd4)

Recombinant Mouse Abhydrolase domain-containing protein 4 (Abhd4)

  • 中文名称：
    Recombinant Mouse Abhydrolase domain-containing protein 4(Abhd4),Yeast
  • 货号：
    CSB-YP823742MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Abhydrolase domain-containing protein 4(Abhd4),Yeast
  • 货号：
    CSB-EP823742MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Abhydrolase domain-containing protein 4(Abhd4),Yeast
  • 货号：
    CSB-EP823742MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Abhydrolase domain-containing protein 4(Abhd4),Yeast
  • 货号：
    CSB-BP823742MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Abhydrolase domain-containing protein 4(Abhd4),Yeast
  • 货号：
    CSB-MP823742MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Abhd4
  • Uniprot No.：
  • 别名：
    Abhd4(Lyso)-N-acylphosphatidylethanolamine lipase; EC 3.1.1.-; Alpha/beta hydrolase domain-containing protein 4; Abhydrolase domain-containing protein 4; Alpha/beta-hydrolase 4
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-342
  • 氨基酸序列
    MADDLEQQPQ GWLSSWLPTW RPTSMSQLKN VEARILQCLQ NKFLARYVSL PNQNKIWTVT VSPEQKDRTP LVMVHGFGGG VGLWILNMDS LSARRTLHTF DLLGFGRSSR PTFPRDPEGA EDEFVASIET WRETMGIPTM ILLGHSLGGF LATSYSIKYP ERVKHLILVD PWGFPLRPTD PSEIRAPPTW VKAVASVLGR SNPLAVLRVA GPWGPGLVQR FRPDFKRKFA DFFEDDTISE YIYHCNAQNP SGETAFKAMM ESFGWARRPM LERIHLIRKD VPITMIYGAN TWIDTSTGKK VKMQRPDSYV RDMEIEGASH HVYADQPHIF NAVVEEICNS VD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.
  • 基因功能参考文献：
    1. These findings, taken together, designate ABHD4 as a principal regulator of N-acyl phospholipid metabolism in the mammalian nervous system. PMID: 25853435
    2. Lysophospholipase/phospholipase B (EC 3.1.1.5) specific for N-acyl phosphatidylethanolamine (NAPE) suggesting a role in the biosynthesis of N-acyl ethanolamines including the endocannabinoid anandamide. PMID: 16818490
  • 蛋白家族：
    Peptidase S33 family, ABHD4/ABHD5 subfamily
  • 组织特异性：
    Highest levels in the CNS and in testis, intermediate levels in liver and kidney. Hardly detectable in heart.
  • 数据库链接：

    KEGG: mmu:105501

    STRING: 10090.ENSMUSP00000044134

    UniGene: Mm.28771