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  4. Recombinant Mouse Achaete-scute homolog 3 (Ascl3)

Recombinant Mouse Achaete-scute homolog 3 (Ascl3)

  • 中文名称：
    Recombinant Mouse Achaete-scute homolog 3(Ascl3),Yeast
  • 货号：
    CSB-YP867501MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Achaete-scute homolog 3(Ascl3),Yeast
  • 货号：
    CSB-EP867501MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Achaete-scute homolog 3(Ascl3),Yeast
  • 货号：
    CSB-EP867501MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Achaete-scute homolog 3(Ascl3),Yeast
  • 货号：
    CSB-BP867501MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Achaete-scute homolog 3(Ascl3),Yeast
  • 货号：
    CSB-MP867501MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ascl3
  • Uniprot No.：
  • 别名：
    Ascl3; Mash3; Sgn1Achaete-scute homolog 3; ASH-3; mASH-3; mASH3; bHLH transcriptional regulator Sgn-1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-174
  • 氨基酸序列
    MDTRSYPSPP DRLSVFAESA HLPLSRPFYL DPMVTVHLCP ETPVPASYTD ELPLLPFSSD TLIMNNYGDP YPFPFPMPYT NYRRCDYTYG PAFIRKRNER ERQRVKCVNE GYARLRRHLP EDYLEKRLSK VETLRAAIKY ISYLQSLLYP DESETKKNPR TASCGSLDPA LRVI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor. Inhibits myogenesis.
  • 基因功能参考文献：
    1. These results demonstrate that Ascl3 marks progenitors that are lineage-committed strictly to microvillar cells and Bowman's glands, and highlight the requirement for these cell types to support OE homeostasis. PMID: 27910949
    2. Ascl3 knockouts develop smaller salivary glands than wild types, but secrete saliva normally. They display a lower level of cell proliferation, consistent with their smaller size. In the absence of Ascl3, the cells maintain their progenitor function. PMID: 21377457
    3. These data demonstrate a progenitor-progeny relationship between duct cells and the acinar cell compartment, and identify a population of multipotent progenitor cells, marked by expression of Ascl3, which is capable of generating both gland cell types. PMID: 18572159
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Specifically expressed in the salivary duct cells.
  • 数据库链接：

    KEGG: mmu:56787

    STRING: 10090.ENSMUSP00000037702

    UniGene: Mm.29275