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Recombinant Mouse Akirin-2 (Akirin2)

  • 中文名称：
    Recombinant Mouse Akirin-2(Akirin2),Yeast
  • 货号：
    CSB-YP001536MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Akirin-2(Akirin2),Yeast
  • 货号：
    CSB-EP001536MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Akirin-2(Akirin2),Yeast
  • 货号：
    CSB-EP001536MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Akirin-2(Akirin2),Yeast
  • 货号：
    CSB-BP001536MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Akirin-2(Akirin2),Yeast
  • 货号：
    CSB-MP001536MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Akirin2
  • Uniprot No.：
  • 别名：
    Akirin2; Akirin-2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-201
  • 氨基酸序列
    MACGATLKRT LDFDPLLSPA SPKRRRCAPL SAPASAAASP AAATAAAAAS AAAASPQKYL RMEPSPFGDV SSRLTTEQIL YNIKQEYKRM QKRRHLEASF QQADPGCTSD SQPHAFLISG PASPGTSSAT SSPLKKEQPL FTLRQVGMIC ERLLKEREEK VREEYEEILN TKLAEQYDAF VKFTHDQIMR RYGEQPASYV S
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Forms a complex with YWHAB that acts to repress transcription of DUSP1. Required for embryonic development and the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6.
  • 基因功能参考文献：
    1. this review discusses current understanding of the molecular mechanisms that have instrumental roles in governing the inflammatory response with special emphasis on Akirin2 in B cells PMID: 28605346
    2. Data demonstrate a previously-unsuspected role for Akirin2 in early cortical development and, given its known nuclear roles, suggest that it may act to regulate gene expression patterns critical for early progenitor cell behavior and cortical neuron production. PMID: 27871306
    3. The nuclear protein akirin2 has an essential function in B cell activation and humoral immune responses. PMID: 26041538
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Akirin family
  • 数据库链接：

    KEGG: mmu:433693

    STRING: 10090.ENSMUSP00000081322

    UniGene: Mm.389532