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  4. Recombinant Mouse Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Aimp2)

Recombinant Mouse Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Aimp2)

  • 中文名称：
    Recombinant Mouse Aminoacyl tRNA synthase complex-interacting multifunctional protein 2(Aimp2),Yeast
  • 货号：
    CSB-YP819153MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Aminoacyl tRNA synthase complex-interacting multifunctional protein 2(Aimp2),Yeast
  • 货号：
    CSB-EP819153MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Aminoacyl tRNA synthase complex-interacting multifunctional protein 2(Aimp2),Yeast
  • 货号：
    CSB-EP819153MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Aminoacyl tRNA synthase complex-interacting multifunctional protein 2(Aimp2),Yeast
  • 货号：
    CSB-BP819153MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Aminoacyl tRNA synthase complex-interacting multifunctional protein 2(Aimp2),Yeast
  • 货号：
    CSB-MP819153MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Aimp2
  • Uniprot No.：
  • 别名：
    Aimp2; Jtv1; Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Multisynthase complex auxiliary component p38; Protein JTV-1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-320
  • 氨基酸序列
    MPMYQVKPYH GGSAPLHVEL PTCMYRLPNV HSKTTSPATD AGHVQETSEP SLQALESRQD DILKRLYELK AAVDGLSKMI HTPDADLDVT NILQADEPTT LATNTLDLNS VLGKDYGALK DIVINANPAS PPLSLLVLHR LLCERYRVLS TVHTHSSVKN VPENLVKCFG EQARKQSRHE YQLGFTLIWK NVPKTQMKFS VQTMCPIEGE GNIARFLFSL FGQKHNAVTL TLIDSWVDIA MFQLREGSSK EKAAVFRSMN SALGRSPWLV GNELTVADVV LWSVLQQTGG SSGAAPTNVQ RWLKSCENLA PFSTALQLLK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
  • 基因功能参考文献：
    1. our findings show how DX2 promotes lung cancer progression and how its activity may be thwarted as a strategy to treat patients with lung cancers exhibiting elevated DX2 levels PMID: 27302160
    2. functional significance of AIMP2 in determination of cell proliferation and death, and as a haploinsufficient tumor suppressor. PMID: 19622630
  • 亚细胞定位：
    Cytoplasm, cytosol. Nucleus.
  • 数据库链接：

    KEGG: mmu:231872

    STRING: 10090.ENSMUSP00000031613

    UniGene: Mm.200499