Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Mouse BarH-like 2 homeobox protein (Barhl2)

Recombinant Mouse BarH-like 2 homeobox protein (Barhl2)

  • 中文名称：
    Recombinant Mouse BarH-like 2 homeobox protein(Barhl2),Yeast
  • 货号：
    CSB-YP848716MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse BarH-like 2 homeobox protein(Barhl2),Yeast
  • 货号：
    CSB-EP848716MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse BarH-like 2 homeobox protein(Barhl2),Yeast
  • 货号：
    CSB-EP848716MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse BarH-like 2 homeobox protein(Barhl2),Yeast
  • 货号：
    CSB-BP848716MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse BarH-like 2 homeobox protein(Barhl2),Yeast
  • 货号：
    CSB-MP848716MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Barhl2
  • Uniprot No.：
  • 别名：
    Barhl2; Barh1; Mbh1BarH-like 2 homeobox protein; Bar-class homeodomain protein MBH1; Homeobox protein B-H1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-384
  • 氨基酸序列
    MTAMEGASGS SFGIDTILSG AGSGSPGMMN GDFRSLGEAR TTDFRSQATP SPCSEIDTVG TAPSSPISVT LEPPEPHLVT DGPQHHHHLH HSQQPPPPSA VPAQSLQPSP QQQPPPQPQS AAQQLGSAAA APRTSTSSFL IKDILGDSKP LAACAPYSTS VSSPHHTPKQ ESNAAHESFR PKLEQEDGKT KLDKREDPQS DIKCHGTKEE GDREITSSRE SPPVRAKKPR KARTAFSDHQ LNQLERSFER QKYLSVQDRM DLAAALNLTD TQVKTWYQNR RTKWKRQTAV GLELLAEAGN YSALQRMFPS PYFYHPSLLG SMDSTTAAAA AAAMYSSMYR TPPAPHPQLQ RPLVPRVLIH GLGPGGQPAL NPLSNPIPGT PHPR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Potential regulator of neural basic helix-loop-helix genes. It may down-regulate expression of ASCL1 and, within the thalamus, up-regulate NGN2, thereby regulating distinct patterns of neuronal differentiation.
  • 基因功能参考文献：
    1. by acting upstream of Shh signaling pathway, Barhl2 plays a crucial role in patterning the progenitor domains and establishing the positional identities of progenitor cells in the diencephalon. PMID: 27349434
    2. The expression of Barhl2 in the thalamus and pretectum is related to, and regulated by, the expression of Pax6. Pax6 is known to be required for normal diencephalic development. The findings suggest that some of its actions might be mediated by its maintenance of a repressive influence over Barhl2 expression in the thalamus and pretectum. PMID: 27887593
    3. results elucidate BARHL2 as a critical postmitotic regulator of dI1 subtype diversification, as well as its intermediate position in the dI1 genetic hierarchy PMID: 22307612
    4. in the developing diencephalon, Caspase3 acts downstream of Barhl2 in limiting neuroepithelial cell proliferation by inhibiting beta-catenin activation. PMID: 21262809
    5. Data suggest that Barhl2 may function to specify the identity of glycinergic amacrine cells from competent progenitors during retinogenesis. PMID: 14998930
    6. Math1 directly regulates the Mbh genes in CGCs. Furthermore, a dominant-negative form of the Mbh proteins disrupted proper PMID: 18723012
    7. BARHL2 plays roles in retinal development, including regulating neuronal subtype specification, differentiation, and survival. PMID: 19339595

    显示更多

    收起更多

  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    BAR homeobox family
  • 数据库链接：

    KEGG: mmu:104382

    STRING: 10090.ENSMUSP00000084005

    UniGene: Mm.271593