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  4. Recombinant Mouse Chitinase-3-like protein 4 (Chi3l4)

Recombinant Mouse Chitinase-3-like protein 4 (Chi3l4)

  • 中文名称：
    Recombinant Mouse Chitinase-like protein 4(Chil4),Yeast
  • 货号：
    CSB-YP842057MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Chitinase-like protein 4(Chil4),Yeast
  • 货号：
    CSB-EP842057MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Chitinase-like protein 4(Chil4),Yeast
  • 货号：
    CSB-EP842057MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Chitinase-like protein 4(Chil4),Yeast
  • 货号：
    CSB-BP842057MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Chil4
  • Uniprot No.：
  • 别名：
    Chil4; Chi3l4; Ym2Chitinase-like protein 4; Chitinase-3-like protein 4; Secreted protein Ym2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    22-402
  • 氨基酸序列
    YQLMCYYTS WAKDRPTEGS FKPGNIDPCL CTHLIYAFAG MKNNEITYLS EQDLRDYEAL NGLKDRNTEL KTLLAIGGWK FGPAPFSSMV STPQNRQTFI KSVIRFLRQY NFDGLNLDWQ YPGSRGSPPK DKHLFSVLVQ EMRKAFEEES TLNHIPRLLL TSTGAGFIDV IKSGYKIPEL SQSLDYIQVM TYDLHDPKNG YTGENSPLYK SPYDIGKSAD LNVDSIITYW KDHGAASEKL IVGFPAYGHT FILSDPSKNG IGDPTVSAGP PGKYTNEQGL LAYFEICTFL NEGATEIFDA TQEVPYAYLG NEWVGYDNVR SFKLKAQWLK DNNLGGAVVW PLDMDDFSGS FCHQGRFPLT TTLKRDLNVH SASCKASYRG EL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Has low chemotactic activity for eosinophils. May play a role in inflammation and allergy. Has no chitinase activity.
  • 基因功能参考文献：
    1. Induced only in the presence of IL-4. PMID: 16174095
    2. Quantitative RT-PCR demonstrated a 976-fold increase of Chi3l4 mRNA expression and a 24-fold increase of Chi3l3 mRNA expression in the skin of cpdm/cpdm mice. PMID: 16984263
    3. Production of Ym1/2 in response to interleukin-13 promotes T helper type (Th)2 cell cytokine production and allergic airway inflammation by inhibiting the production of 12(S)-hydroxyeicosatetraenoic acid (HETE) by 12/15(S)-lipoxygenase (LOX). PMID: 19380786
    4. The eosinophilic protein Ym2 (chitinase 3-like 4) was isolated from characteristic hyaline gastric lesion mainly found in female CYP1A2-null mice. The relation between Ym2 and CYP1A2 is unknown. PMID: 11141507
  • 亚细胞定位：
    Secreted. Cytoplasm. Note=Detected in the cytoplasm of keratinocytes.
  • 蛋白家族：
    Glycosyl hydrolase 18 family, Chitinase class II subfamily
  • 组织特异性：
    Detected in stratified squamous epithelium in the junctional region between forestomach and glandular stomach (at protein level). Expression is mainly restricted to stomach.
  • 数据库链接：

    KEGG: mmu:104183

    STRING: 10090.ENSMUSP00000080851

    UniGene: Mm.425140