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  4. Recombinant Mouse Complement C1q subcomponent subunit B (C1qb)

Recombinant Mouse Complement C1q subcomponent subunit B (C1qb)

  • 货号：
    CSB-YP003638MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP003638MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-BP003638MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP003638MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    C1qbComplement C1q subcomponent subunit B
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    26-253
  • 氨基酸序列
    QSSCT GPPGIPGIPG VPGVPGSDGQ PGTPGIKGEK GLPGLAGDLG EFGEKGDPGI PGTPGKVGPK GPVGPKGTPG PSGPRGPKGD SGDYGATQKV AFSALRTINS PLRPNQVIRF EKVITNANEN YEPRNGKFTC KVPGLYYFTY HASSRGNLCV NLVRGRDRDS MQKVVTFCDY AQNTFQVTTG GVVLKLEQEE VVHLQATDKN SLLGIEGANS IFTGFLLFPD MDA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
  • 基因功能参考文献：
    1. The mRNA levels of H2-d1 in the prefrontal cortex, hippocampus, and hypothalamus and C1qb in the hippocampus of the DBA/2 J strain were significantly down-regulated as compared to those in the C57BL/6 J strain PMID: 25895500
  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Highest expression in thioglycolate-activated peritoneal macrophages. Also found in spleen, thymus and heart. Very weak expression liver, kidney, lung and intestine.
  • 数据库链接：

    KEGG: mmu:12260

    STRING: 10090.ENSMUSP00000040246

    UniGene: Mm.2570