C1qb
C1QB,即Complement C1q Subcomponent B,是血清补体系统C1复合体的一个组成部分。C1QB与C1QA和C1QC链一起,与C1r和C1s两种前体酶结合,形成C1,这是血清补体系统的第一个组分。C1QB由18条多肽链组成,包括6条A链、6条B链和6条C链,每条链都包含一个N端胶原样区域和一个C端C1q球形域。C1QB的作用机制涉及其球形头部与免疫复合物的Fc区域相互作用,触发补体级联反应,导致对病原体的攻击和清除。C1QB在宿主防御中起着至关重要的作用,它参与免疫复合物的识别和清除,促进吞噬作用,调节细胞因子产生,影响T淋巴细胞成熟。此外,C1QB还涉及组织修复、肿瘤免疫监视以及中枢神经系统的稳态调节。C1QB的功能对于维持免疫平衡和预防自身免疫疾病具有重要意义,其在多种生理和病理过程中的作用表明了其在免疫调节和细胞过程中的复杂角色。
热销产品
Recombinant Mouse Complement C1q subcomponent subunit B (C1qb), Biotinylated (CSB-EP003638MO-B)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
C1QB Antibody (CSB-PA003638ESR1HU)
验证数据
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA003638ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA003638ESR1HU at dilution of 1:100
C1qb Antibodies
C1qb for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA003638ESR1HU | C1QB Antibody | Human | ELISA, IHC |
CSB-PA197114 | C1QB Antibody | Human | ELISA,WB,IHC,IF |
CSB-PA001087 | C1QB Antibody | Human | WB, IHC, IF, ELISA |
C1qb Proteins
C1qb Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP003638MO CSB-EP003638MO CSB-BP003638MO CSB-MP003638MO |
Recombinant Mouse Complement C1q subcomponent subunit B (C1qb) | Yeast E.coli Baculovirus Mammalian cell |
C1qb Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP003638RA CSB-EP003638RA CSB-BP003638RA CSB-MP003638RA CSB-EP003638RA-B |
Recombinant Rat Complement C1q subcomponent subunit B (C1qb) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
C1qb Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP003638HU CSB-EP003638HU CSB-BP003638HU CSB-MP003638HU CSB-EP003638HU-B |
Recombinant Human Complement C1q subcomponent subunit B (C1QB) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
C1qb Proteins for Bos taurus (Bovine)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP640677BO CSB-EP640677BO CSB-BP640677BO CSB-MP640677BO CSB-EP640677BO-B |
Recombinant Bovine Complement C1q subcomponent subunit B (C1QB) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
C1qb ELISA Kit
C1qb ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E10118h | Human Complement 1q,C1q ELISA Kit | serum, plasma, tissue homogenates | 0.039 ng/mL |