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C1qb

C1QB,即Complement C1q Subcomponent B,是血清补体系统C1复合体的一个组成部分。C1QB与C1QA和C1QC链一起,与C1r和C1s两种前体酶结合,形成C1,这是血清补体系统的第一个组分。C1QB由18条多肽链组成,包括6条A链、6条B链和6条C链,每条链都包含一个N端胶原样区域和一个C端C1q球形域。C1QB的作用机制涉及其球形头部与免疫复合物的Fc区域相互作用,触发补体级联反应,导致对病原体的攻击和清除。C1QB在宿主防御中起着至关重要的作用,它参与免疫复合物的识别和清除,促进吞噬作用,调节细胞因子产生,影响T淋巴细胞成熟。此外,C1QB还涉及组织修复、肿瘤免疫监视以及中枢神经系统的稳态调节。C1QB的功能对于维持免疫平衡和预防自身免疫疾病具有重要意义,其在多种生理和病理过程中的作用表明了其在免疫调节和细胞过程中的复杂角色。

热销产品

Recombinant Mouse Complement C1q subcomponent subunit B (C1qb), Biotinylated (CSB-EP003638MO-B)

验证数据

CSB-EP003638MO-B

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

C1QB Antibody (CSB-PA003638ESR1HU)

验证数据

CSB-PA003638ESR1HU

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA003638ESR1HU at dilution of 1:100

CSB-PA003638ESR1HU

Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA003638ESR1HU at dilution of 1:100

C1qb Antibodies

C1qb for Homo sapiens (Human)

C1qb Proteins

C1qb Proteins for Mus musculus (Mouse)

C1qb Proteins for Rattus norvegicus (Rat)

C1qb Proteins for Homo sapiens (Human)

C1qb Proteins for Bos taurus (Bovine)

C1qb ELISA Kit

C1qb ELISA Kit for Homo sapiens (Human)