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  4. Recombinant Mouse Developmental pluripotency-associated protein 2 (Dppa2)

Recombinant Mouse Developmental pluripotency-associated protein 2 (Dppa2)

  • 中文名称：
    小鼠Dppa2重组蛋白
  • 货号：
    CSB-YP861473MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Dppa2重组蛋白
  • 货号：
    CSB-EP861473MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Dppa2重组蛋白
  • 货号：
    CSB-EP861473MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Dppa2重组蛋白
  • 货号：
    CSB-BP861473MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Dppa2重组蛋白
  • 货号：
    CSB-MP861473MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Dppa2
  • Uniprot No.：
  • 别名：
    Dppa2; Phsecrg1; Developmental pluripotency-associated protein 2; Embryonic stem cell-associated transcript 15-2 protein; ECAT15-2; Pluripotent embryonic stem cell-related gene 1 protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-301
  • 氨基酸序列
    MSYFGLETFN ENQSEENLDE ESVILTLVPF KEEEEPNTDY ATQSNVSSST LDHTPPARSL VRHAGIKHPT RTIPSTCPPP SLPPIRDVSR NTLREWCRYH NLSTDGKKVE VYLRLRRHSY SKQECYIPNT SREARMKQGP KKSKIVFRGI GPPSGCQRKK EESGVLEILT SPKESTFAAW ARIAMRAAQS MSKNRCPLPS NVEAFLPQAT GSRWCVVHGR QLPADKKGWV RLQFLAGQTW VPDTPQRMNF LFLLPACIIP EPGVEDNLLC PECVHSNKKI LRNFKIRSRA KKNALPPNMP P
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes.
  • 基因功能参考文献：
    1. a novel long non-coding RNA was found to silence its neighboring gene, Dppa2, in cis through recruiting Dnmt1, Dnmt3a and Dnmt3b PMID: 25686699
    2. Results identified a new family of pluripotency-related oncogenes consisting of DPPA2 and DPPA4. PMID: 23963736
    3. has important roles in lung development, where it is no longer expressed, by leaving epigenetic marks from earlier developmental stages PMID: 21896782
    4. Results showed that the expression of Dppa2 decreased markedly in differentiated cells. Dppa2 might play a role in maintenance of the undifferentiated state and proliferation of ES cells PMID: 19846433
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Not detected in adult tissues.
  • 数据库链接：

    KEGG: mmu:73703

    STRING: 10090.ENSMUSP00000110183

    UniGene: Mm.27857