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  4. Recombinant Mouse Dual specificity protein phosphatase 7 (Dusp7)

Recombinant Mouse Dual specificity protein phosphatase 7 (Dusp7)

  • 中文名称：
    小鼠Dusp7重组蛋白
  • 货号：
    CSB-YP842055MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Dusp7重组蛋白
  • 货号：
    CSB-EP842055MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Dusp7重组蛋白
  • 货号：
    CSB-EP842055MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Dusp7重组蛋白
  • 货号：
    CSB-BP842055MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Dusp7重组蛋白
  • 货号：
    CSB-MP842055MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Dusp7Dual specificity protein phosphatase 7; EC 3.1.3.16; EC 3.1.3.48
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-422
  • 氨基酸序列
    MKNQLRGPPV RAHMSTSGAA AAAAAGGTRA GSEPGAGSGS GAGIGAGATT GAGAMPCKSA EWLQEELEAR GGASLLLLDC RPHELFESSH IETAINLAIP GLMLRRLRKG NLPIRSIIPN HADKERFATR CKAATVLLYD EATAEWQPEP GAPASVLGLL LQKLRDDGCQ AYYLQGGFNK FQTEYSEHCE TNVDSSSSPS GSPPTSVLGL GGLRISSDCS DGESDRELPS SATESDGSPV PSSQPAFPVQ ILPYLYLGCA KDSTNLDVLG KYGIKYILNV TPNLPNAFEH GGEFTYKQIP ISDHWSQNLS QFFPEAISFI DEARSKKCGV LVHCLAGISR SVTVTVAYLM QKMNLSLNDA YDFVKRKKSN ISPNFNFMGQ LLDFERTLGL SSPCDNHAPS EQLYFSTPTN HNLFPINTLE ST
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Dual specificity protein phosphatase. Shows high activity towards MAPK1/ERK2. Also has lower activity towards MAPK14 and MAPK8. In arrested oocytes, plays a role in meiotic resumption. Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complex in oocytes, probably by dephosphorylating and inactivating the conventional protein kinase C (cPKC) isozyme PRKCB. May also inactivate PRKCA and/or PRKCG. Also important in oocytes for normal chromosome alignment on the metaphase plate and progression to anaphase, where it might regulate activity of the spindle-assembly checkpoint (SAC) complex.
  • 基因功能参考文献：
    1. DUSP7 is an essential regulator of multiple steps in oocyte meiosis. PMID: 27783954
    2. Data show that Dusp7 transcripts is expressed in partially overlapping patterns that correspond to regions of active FGF signaling, suggesting combinatorial roles in negative regulation of this pathway during ear development. PMID: 18058922
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
  • 数据库链接：

    KEGG: mmu:235584

    STRING: 10090.ENSMUSP00000126984

    UniGene: Mm.275584