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  4. Recombinant Mouse GTPase IMAP family member 3 (Gimap3), partial

Recombinant Mouse GTPase IMAP family member 3 (Gimap3), partial

  • 中文名称：
    小鼠Gimap3重组蛋白
  • 货号：
    CSB-YP860822MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Gimap3重组蛋白
  • 货号：
    CSB-EP860822MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Gimap3重组蛋白
  • 货号：
    CSB-EP860822MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Gimap3重组蛋白
  • 货号：
    CSB-BP860822MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Gimap3重组蛋白
  • 货号：
    CSB-MP860822MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Gimap3
  • Uniprot No.：
  • 别名：
    Gimap3; Ian4GTPase IMAP family member 3; Immunity-associated nucleotide 4 protein; IAN-4
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    During thymocyte development, may support the positive selection of CD4 and CD8 T cells. May play a role in mitochondrial DNA segregation in hematopoietic tissues. Binds GTP.
  • 基因功能参考文献：
    1. quantitative changes in expression of Gimap3 and the paralogue Gimap5 affect mtDNA segregation in hematopoietic tissues. Gimap3 localizes to the endoplasmic reticulum and not mitochondria. PMID: 25808953
    2. The defects in T-cell cellularity were more severe in mice lacking both Gimap3 and Gimap5. PMID: 24510501
    3. Data shsow that Gimap3 is important for T cell development and survival, suggesting that leukocyte survival may be a key factor in the genetic regulation of mtDNA sequence variants and in modulating human mitochondrial diseases. PMID: 20976251
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
  • 蛋白家族：
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, AIG1/Toc34/Toc159-like paraseptin GTPase family, IAN subfamily
  • 组织特异性：
    Expressed in thymus (in thymocytes), spleen (in splenocytes), lymph node and, at lower levels, in lung. Highly expressed in T lymphocytes.
  • 数据库链接：

    KEGG: mmu:83408

    STRING: 10090.ENSMUSP00000047435

    UniGene: Mm.333050