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  4. Recombinant Mouse Glutathione S-transferase theta-1 (Gstt1)

Recombinant Mouse Glutathione S-transferase theta-1 (Gstt1)

  • 中文名称：
    小鼠Gstt1重组蛋白
  • 货号：
    CSB-YP734107MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Gstt1重组蛋白
  • 货号：
    CSB-EP734107MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Gstt1重组蛋白
  • 货号：
    CSB-EP734107MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Gstt1重组蛋白
  • 货号：
    CSB-BP734107MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Gstt1重组蛋白
  • 货号：
    CSB-MP734107MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Gstt1
  • Uniprot No.：
  • 别名：
    Gstt1; Glutathione S-transferase theta-1; EC 2.5.1.18; GST class-theta-1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-240
  • 氨基酸序列
    VLELYLDLL SQPCRAIYIF AKKNNIPFQM HTVELRKGEH LSDAFARVNP MKRVPAMMDG GFTLCESVAI LLYLAHKYKV PDHWYPQDLQ ARARVDEYLA WQHTGLRRSC LRALWHKVMF PVFLGEQIPP ETLAATLAEL DVNLQVLEDK FLQDKDFLVG PHISLADLVA ITELMHPVGG GCPVFEGHPR LAAWYQRVEA AVGKDLFREA HEVILKVKDC PPADLIIKQK LMPRVLAMIQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity.
  • 基因功能参考文献：
    1. minor structural changes in the C-terminal helix of mouse GST T1-1 induce major changes in the substrate-activity profile of the enzyme to favor novel chemical reactions and to suppress other reactions catalyzed by the parental enzyme PMID: 20022951
    2. The carcinogenic effects of DCM in the mouse are caused by the interaction with DNA of a glutathione (GSH) conjugate that is produced by the class theta glutathione S-transferase T1-1 (GST T1-1). PMID: 11884241
    3. Gstt1-null mice would be useful as an animal model of humans with the GSTT1-null genotype. PMID: 17827337
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    GST superfamily, Theta family
  • 组织特异性：
    In liver, highest expression found in central vein limiting plate hepatocytes. Also expressed in interlobular bile duct epithelial cells. In lung, expressed in Clara cells and ciliated cells of the bronchiolar epithelium and in type II alveolar cells of t
  • 数据库链接：

    KEGG: mmu:14871

    STRING: 10090.ENSMUSP00000001713

    UniGene: Mm.2746