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  4. Recombinant Mouse Intraflagellar transport protein 81 homolog (Ift81)

Recombinant Mouse Intraflagellar transport protein 81 homolog (Ift81)

  • 中文名称：
    小鼠Ift81重组蛋白
  • 货号：
    CSB-YP011079MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Ift81重组蛋白
  • 货号：
    CSB-EP011079MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Ift81重组蛋白
  • 货号：
    CSB-EP011079MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Ift81重组蛋白
  • 货号：
    CSB-BP011079MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Ift81重组蛋白
  • 货号：
    CSB-MP011079MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ift81
  • Uniprot No.：
  • 别名：
    Ift81; Cdv-1; Cdv1Intraflagellar transport protein 81 homolog; Carnitine deficiency-associated protein expressed in ventricle 1; CDV-1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-676
  • 氨基酸序列
    SDQIKFIVD SLNKEPFKKN YNLITFDSLG PMQLLQVLND VLAEIDPKQD VDIREEMPEQ TAKRMLNLLG ILKYKPPGNA TDMSTFRQGL VIGSKPVIYP VLHWLLQRSN ELKKRAYLAR FLIKLEVPSE FLQDETVADT NKQYEELMEA FKTLHKECEQ LKTSGFSTAE IRRDISAMEE EKDQLMKRVE RLKKRVETVQ NHQRMLKIAR QLRVEKEREE FLAQQKQEQK NQLFHAVQRL QRVQNQLKSM RHAAADAKPE SLMKRLEEEI KFNSYMVTEK FPKELESKKK ELHFLQKVVS EPAMGHSDLL ELETKVNEVN TEINQLIEKK MMRNEPIEGK LSLYRQQASI ISRKKEAKAE ELQETKEKLA SLEREVLVKT NQTREFDGTE VLKGDEFKRY VSKLRSKSTV FKKKHQIIAE FKAEFGLLQR TEELLKQRQE TIQHQLRTIE EKKGISGYSY TQEELERVSA LKSEVDEMKG RTLDDMSEMV KKLNSLVSEK KSALAPVIKE LRQLRQKCQE LTQECDEKKA QYDSCAAGLE SNRSKLEQEV RGLREECLQE ESKYHYTNCM IKNLEVELRR ATDEMKAYVS SDQQEKRKAI REQYTKNITE QENLGKKLRE KQKAVRESHG PNMKQAKMWR DLEQLMECKK QCFLKQQSPA SIGQVIQEGG EDRLVL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis. Required for proper regulation of SHH signaling.; May be involved in cardiac hypertrophy caused by carnitine deficiency.; May play a role in development of the testis and spermatogenesis.
  • 基因功能参考文献：
    1. inconsistent expression levels of human CDV-1 and mouse Cdv-1 in heart implied that cardiac hypertrophy in human SCD might not be associated with the abnormal expression of CDV-1. PMID: 12549821
    2. Cdv-1R might be involved in the carnitine pathway in the epididimis PMID: 15764413
  • 亚细胞定位：
    Cell projection, cilium.
  • 蛋白家族：
    IFT81 family
  • 组织特异性：
    Isoform CDV-1 is expressed specifically in heart and suppressed specifically in ventricles, but not in auricles, of carnitine-deficient juvenile visceral steatosis (JVS) mice. Isoform CDV-1R is expressed predominantly in the testis. Co-localizes with RABL
  • 数据库链接：

    KEGG: mmu:12589

    STRING: 10090.ENSMUSP00000031426

    UniGene: Mm.10125