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  4. Recombinant Mouse Low molecular weight phosphotyrosine protein phosphatase (Acp1)

Recombinant Mouse Low molecular weight phosphotyrosine protein phosphatase (Acp1)

  • 中文名称：
    Recombinant Mouse Low molecular weight phosphotyrosine protein phosphatase(Acp1),Yeast
  • 货号：
    CSB-YP875197MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Low molecular weight phosphotyrosine protein phosphatase(Acp1),Yeast
  • 货号：
    CSB-EP875197MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Low molecular weight phosphotyrosine protein phosphatase(Acp1),Yeast
  • 货号：
    CSB-EP875197MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Low molecular weight phosphotyrosine protein phosphatase(Acp1),Yeast
  • 货号：
    CSB-BP875197MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Low molecular weight phosphotyrosine protein phosphatase(Acp1),Yeast
  • 货号：
    CSB-MP875197MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Acp1
  • Uniprot No.：
  • 别名：
    Acp1; Low molecular weight phosphotyrosine protein phosphatase; LMW-PTP; LMW-PTPase; EC 3.1.3.48; Low molecular weight cytosolic acid phosphatase; EC 3.1.3.2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-158
  • 氨基酸序列
    AEVGSKSVL FVCLGNICRS PIAEAVFRKL VTDEKVSDNW RIDSAATSTY EVGNPPDYRG QNCMRKHGIH MQHIARQITK EDFATFDYIL CMDESNLRDL NRKSNQVKNC KAKIELLGSY DPQKQLIIED PYYGNDSDFE VVYQQCLRCC KAFLEKTY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
  • 基因功能参考文献：
    1. Our data show that ablation of Lmptp inhibits pathological cardiac remodelling PMID: 26213100
    2. Data indicate there was no significant change in low molecular weight protein tyrosine phosphatase (LMW-PTP) expression at 30 min or 2 h. PMID: 24123071
    3. low M(r) phosphotyrosine protein phosphatase participation in FAK-mediated focal adhesion remodeling. PMID: 12055185
    4. plays a role on PDGF receptor signaling and controls PDGF-r kinase activity through TYR-857 dephosphorylation PMID: 12149261
    5. The redox-dependent enhancement of Grb2 recruitment to LMW-PTP ultimately leads to an improvement of ERK activation, likely triggering a prosurvival signal against the oxidant environment. PMID: 16890200
    6. The formation of LMW-PTP/caveolin-1 complexes is accompanied by modulation of the enzyme activities, and the inhibitory effect elicited against IF1 is stronger than that against IF2 PMID: 17469800
    7. The expression and activity of Src and low molecular weight protein tyrosine phosphatase (LMWPTP) during osteoblast differentiation was examined and the modulation of Src kinase by LMWPTP was assessed. PMID: 19088431

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Low molecular weight phosphotyrosine protein phosphatase family
  • 组织特异性：
    Widely expressed with highest levels in brain and liver and lowest levels in muscle.
  • 数据库链接：

    KEGG: mmu:11431

    UniGene: Mm.359831