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  4. Recombinant Mouse Netrin receptor UNC5D (Unc5d), partial

Recombinant Mouse Netrin receptor UNC5D (Unc5d), partial

  • 中文名称：
    小鼠Unc5d重组蛋白
  • 货号：
    CSB-YP815649MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Unc5d重组蛋白
  • 货号：
    CSB-EP815649MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Unc5d重组蛋白
  • 货号：
    CSB-EP815649MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Unc5d重组蛋白
  • 货号：
    CSB-BP815649MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Unc5d重组蛋白
  • 货号：
    CSB-MP815649MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Unc5d
  • Uniprot No.：
  • 别名：
    Unc5d; Unc5h4; Netrin receptor UNC5D; Protein unc-5 homolog 4; Protein unc-5 homolog D
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Receptor for the netrin NTN4 that promotes neuronal cell survival. Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in the regulation of neuronal cell migration in the developing brain via its interaction with FLRT2. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell.
  • 基因功能参考文献：
    1. Data show that Unc5 cell guidance receptor Unc5D controls Latrophilin3 (LPHN3)-FLRT protein FLRT2-mediated cell adhesion. PMID: 27091502
    2. Unc5d is primarily expressed by layer 4 cells in the primary sensory areas of the developing neocortex and may mediate the effect of netrin-4 on cortical cell survival in a lamina-specific manner. PMID: 21216843
    3. Unc5h4 was cloned; its expression is in the developing limb and mammary gland in developing mouse PMID: 12351186
    4. UNC5D protein and nuclear RNA is localized in the multipolar cells of the subventricular zone throughout cortical development. PMID: 18547816
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Unc-5 family
  • 组织特异性：
    Detected in multipolar cells in the brain subventricular zone (at protein level). Detected in embryonic brain neocortex, especially in the subventricular zone. Detected in multipolar cells in the brain subventricular zone. Detected in brain neocortex from
  • 数据库链接：

    KEGG: mmu:210801

    STRING: 10090.ENSMUSP00000128521

    UniGene: Mm.248433