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  4. Recombinant Mouse Probable tubulin polyglutamylase TTLL9 (Ttll9)

Recombinant Mouse Probable tubulin polyglutamylase TTLL9 (Ttll9)

  • 中文名称：
    小鼠Ttll9重组蛋白
  • 货号：
    CSB-YP025266MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Ttll9重组蛋白
  • 货号：
    CSB-EP025266MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Ttll9重组蛋白
  • 货号：
    CSB-EP025266MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Ttll9重组蛋白
  • 货号：
    CSB-BP025266MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Ttll9重组蛋白
  • 货号：
    CSB-MP025266MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ttll9
  • Uniprot No.：
  • 别名：
    Ttll9; Probable tubulin polyglutamylase TTLL9; EC 6.-.-.-; Tubulin--tyrosine ligase-like protein 9
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-461
  • 氨基酸序列
    MSRQKNQNSK GHGVSKGKER EQRTLIRFKT TLMNTLMDVL RHRPGWVEVK DEGEWDFYWC DVSWLRENFD HTYMDEHVRI SHFRNHYELT RKNYMVKNLK RFRKYLERES GKTEAAKCDF FPKTFEMPCE YHLFVEEFRK NPGITWIMKP VARSQGKGIF LFRRLKDIMD WRKGTSGKKP TGVETQPARA NMNPSGSHDT RSSDDQKDDL PVENYVAQRY VENPYLIGGR KFDLRVYVLV MSYIPLRAWL YRDGFARFSN TRFTLNSIDD HYVHLTNVAV QKTSPDYHLK KGCKWMLQRF RQYLASKHGP KAVETLFSDM DNIFIKSLQS VQKVIISDKH CFELYGYDIL IDQDLKPWLL EVNASPSLTA SSQEDYELKT CLLEDTLHVV DMEARLTGKE KRVGGFDLMW NDGPVSREDG PSDLSGMGNF VTNTHLGCVN DRKEQLRQLF RSLQAQRKAP S
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable tubulin polyglutamylase that generates side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of target proteins. Similar to TTLL1, may acquire enzymatic activity only in complex with other proteins as it is most likely lacking domains important for autonomous activity. Mediates tubulin polyglutamylation which induces establishment of microtubule heterogeneity in sperm flagella, thereby playing a role in normal motile flagella axoneme structure and sperm flagella beating pattern.
  • 基因功能参考文献：
    1. Ttll9 plays essential roles in maintaining the normal structure and beating pattern of sperm flagella by establishing normal heterogeneous polyglutamylation patterns. PMID: 27257088
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum axoneme.
  • 组织特异性：
    Highly expressed in brain and testis. Expressed in heart, kidney and lung. In the brain, expressed in ependymal cilia, cortex, corpus callosum and striatum. In the testis, specifically expressed in the seminiferous tubules.
  • 数据库链接：

    KEGG: mmu:74711

    STRING: 10090.ENSMUSP00000099444

    UniGene: Mm.44746