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  4. Recombinant Mouse Procollagen C-endopeptidase enhancer 1 (Pcolce)

Recombinant Mouse Procollagen C-endopeptidase enhancer 1 (Pcolce)

  • 中文名称：
    小鼠Pcolce重组蛋白
  • 货号：
    CSB-YP736817MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Pcolce重组蛋白
  • 货号：
    CSB-EP736817MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Pcolce重组蛋白
  • 货号：
    CSB-EP736817MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Pcolce重组蛋白
  • 货号：
    CSB-BP736817MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Pcolce重组蛋白
  • 货号：
    CSB-MP736817MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Pcolce
  • Uniprot No.：
  • 别名：
    Pcolce; Pcpe1; Procollagen C-endopeptidase enhancer 1; P14; Procollagen COOH-terminal proteinase enhancer 1; PCPE-1; Procollagen C-proteinase enhancer 1; Type 1 procollagen C-proteinase enhancer protein; Type I procollagen COOH-terminal proteinase enhancer
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    25-468
  • 氨基酸序列
    QTPNYT RPVFLCGGDV TGESGYVASE GFPNLYPPNK KCIWTITVPE GQTVSLSFRV FDMELHPSCR YDALEVFAGS GTSGQRLGRF CGTFRPAPVV APGNQVTLRM TTDEGTGGRG FLLWYSGRAT SGTEHQFCGG RMEKAQGTLT TPNWPESDYP PGISCSWHII APSNQVIMLT FGKFDVEPDT YCRYDSVSVF NGAVSDDSKR LGKFCGDKAP SPISSEGNEL LVQFVSDLSV TADGFSASYR TLPRDAVEKE SALSPGEDVQ RGPQSRSDPK TGTGPKVKPP TKPKSQPAET PEASPATQAT PVAPAAPSIT CPKQYKRSGT LQSNFCSSSL VVTGTVKTMV RGPGEGLTVT VSLLGVYKTG GLDLPSPPSG TSLKLYVPCR QMPPMKKGAS YLLMGQVEEN RGPILPPESF VVLYRSNQDQ ILNNLSKRKC PSQPRTAA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.
  • 基因功能参考文献：
    1. Bone morphogenetic protein-1/mTLD and PCPE-1 are upregulated in corneal scars. Both proteins may therefore contribute to the process of corneal scarring. PMID: 25249603
    2. procollagen C-proteinase enhancer-1 (PCPE-1) binds to heparin/heparan sulfate and has a role in interaction with cells PMID: 20729553
    3. PCPE1 and PCPE2 were found to be collagen-binding proteins, capable of binding at multiple sites on the triple helical portions of fibrillar collagens and also capable of competing for such binding with procollagen C-proteinases PMID: 12393877
    4. PCOLCE1 is an important determinant of bone mechanical properties and geometry and of collagen fibril morphology in mammals. PMID: 16354695
  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Expressed in interstitial connective tissues like tendons, calvaria, skin and at a lower level in heart and skeletal muscle.
  • 数据库链接：

    KEGG: mmu:18542

    STRING: 10090.ENSMUSP00000031731

    UniGene: Mm.262345