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  4. Recombinant Mouse Protocadherin-12 (Pcdh12), partial

Recombinant Mouse Protocadherin-12 (Pcdh12), partial

  • 中文名称：
    小鼠Pcdh12重组蛋白
  • 货号：
    CSB-YP017528MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Pcdh12重组蛋白
  • 货号：
    CSB-EP017528MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Pcdh12重组蛋白
  • 货号：
    CSB-EP017528MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Pcdh12重组蛋白
  • 货号：
    CSB-BP017528MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Pcdh12重组蛋白
  • 货号：
    CSB-MP017528MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Pcdh12
  • Uniprot No.：
  • 别名：
    Pcdh12; Protocadherin-12; Vascular cadherin-2; Vascular endothelial cadherin-2; VE-cad-2; VE-cadherin-2) [Cleaved into: Protocadherin-12; secreted form]
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Acts as a regulator of cell migration, probably via increasing cell-cell adhesion. Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton.
  • 基因功能参考文献：
    1. The reactivity to acetylcholine and the circumferential mid-wall stress decreased with ageing in the PCDH12(-/-) mice, as opposed to the increase observed in the wild types. PMID: 22205043
    2. PCDH12 has a unique expression pattern and its deficiency does not lead to conspicuous abnormalities; it is the first specific marker for both glycogen-rich trophoblasts and mesangial cells. PMID: 15541725
    3. Loss of PCDH12 leads to morphological alterations of the placenta and to notable changes in its gene expression profile. PMID: 18477666
  • 亚细胞定位：
    [Protocadherin-12]: Cell membrane; Single-pass type I membrane protein. Cell junction.; [Protocadherin-12, secreted form]: Secreted.
  • 组织特异性：
    Expressed in endothelial cells: localizes in vasculogenic rather than angiogenic endothelium. Strongly expressed in a subset of invasive cells of the placenta, named glycogen-rich trophoblasts cells (at protein level). glycogen-rich trophoblasts cells ori
  • 数据库链接：

    KEGG: mmu:53601

    STRING: 10090.ENSMUSP00000025311

    UniGene: Mm.12862