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  4. Recombinant Mouse Rho GTPase-activating protein 15 (Arhgap15)

Recombinant Mouse Rho GTPase-activating protein 15 (Arhgap15)

  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 15(Arhgap15),Yeast
  • 货号：
    CSB-YP772192MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 15(Arhgap15),Yeast
  • 货号：
    CSB-EP772192MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 15(Arhgap15),Yeast
  • 货号：
    CSB-EP772192MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 15(Arhgap15),Yeast
  • 货号：
    CSB-BP772192MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 15(Arhgap15),Yeast
  • 货号：
    CSB-MP772192MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Arhgap15
  • Uniprot No.：
  • 别名：
    Arhgap15; Rho GTPase-activating protein 15; ArhGAP15; Rho-type GTPase-activating protein 15
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-481
  • 氨基酸序列
    MEKRTSCSVQ TSTNCDNSLE ILNSAHQATG AVQMRIKNAN SHQDRQSQTK SMILTDAGKV TEPISRHRRN HSQHVLKDVI PPLEHPMVEK EGYLQKAKIA DGGKKLRKNW STSWIVLSGR KIEFYKDSKQ QALPNMKTRH NVESVDLCGA HIEWAKEKSS RKSVFQITTV SGNEFLLQSD IDFLILDWFQ AIKNAIDRLP KNPSCGSLEL FNLQRSSSSE LPSHCHIDRK EQKPEHRKSF MFRLHHSASD TSDKNRVKSR LKKFISRRPS LKTLQEKGLI KDQIFGSHLH TVCEREHSTV PWFVKQCIEA VEKRGLDVDG IYRVSGNLAT IQKLRFIVNQ EEKLNLDDSQ WEDIHVVTGA LKMFFRELSE PLFPYSFFER FVEAIKKQDS NEKIETMRSL VKRLPPPNHD TMKILFRHLT KIVAKASQNL MSTQSLGIVF GPTLLRAENE SGNVAVHMVY QNQIAEFMLT EYDKIFSSEE D
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction.
  • 基因功能参考文献：
    1. ArhGAP15 role in the modulation of Rac1/Rac3 activity in the hippocampal inhibitory neurons. PMID: 27713499
    2. these results demonstrate the relevance of ArhGAP15 in the selective regulation of multiple neutrophil functions PMID: 21551229
    3. Arhgap15 is associated with acute lung injury PMID: 21297076
  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 数据库链接：

    KEGG: mmu:76117

    STRING: 10090.ENSMUSP00000056461

    UniGene: Mm.217350