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  4. Recombinant Mouse Secretoglobin family 3A member 1 (Scgb3a1)

Recombinant Mouse Secretoglobin family 3A member 1 (Scgb3a1)

  • 中文名称：
    小鼠Scgb3a1重组蛋白
  • 货号：
    CSB-YP856349MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Scgb3a1重组蛋白
  • 货号：
    CSB-EP856349MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Scgb3a1重组蛋白
  • 货号：
    CSB-EP856349MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Scgb3a1重组蛋白
  • 货号：
    CSB-BP856349MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Scgb3a1重组蛋白
  • 货号：
    CSB-MP856349MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Scgb3a1
  • Uniprot No.：
  • 别名：
    Scgb3a1; Hin1; Pnsp2; Ugrp2; Secretoglobin family 3A member 1; Cytokine HIN-1; High in normal 1; Pneumo secretory protein 2; PnSP-2; Uteroglobin-related protein 2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    22-104
  • 氨基酸序列
    FFMDSLAKP AVEPVAALAP AAEAVAGAVP SLPLSHLAIL RFILASMGIP LDPLIEGSRK CVTELGPEAV GAVKSLLGVL TMFG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Secreted cytokine-like protein. Inhibits cell growth in vitro.
  • 基因功能参考文献：
    1. Neonatal hyperoxia followed by RA recovery was associated with decreased lung CCSP and SCGB3A1 protein but not mRNA expression. PMID: 24187664
    2. The differential expression of mRNA by both airway level and lung region was determined for uteroglobin-related protein 2. PMID: 20852037
    3. Highest HIN-1 and UGRP-1 expression is detected in the lung, while lower level HIN-1 expression is also detected in the stomach, heart, small intestine, uterine and mammary glands PMID: 12175512
    4. genomic structure and expression patterns of Ugrp2 and its alternative spliced form were characterized PMID: 12438750
    5. EGF-induced increase of Ugrp2 occurred at the transcriptional level that required the EGF receptor and the activation of the ERK-MAPK and phosphoinositide-3 kinase pathways PMID: 15811345
    6. ubiquitous transcription factor NF-Y binds to and activates expression of the Scgb3a1 gene and tissue-specific expression of the gene is associated with CpG methylation of the promoter PMID: 18194566
    7. The expression of SCGB3A1 and SCGB3A2 are bidirectionally regulated by oncostatin M (OSM) when examined in a mouse transformed Clara cell line. PMID: 18978304
    8. Expression of SCGB3A1 was down-regulated by IFN-gamma in a time- and dose-dependent manner in the murine transformed Clara Cells line. PMID: 19135978

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Secretoglobin family, UGRP subfamily
  • 组织特异性：
    Highly expressed in lung, where it localizes to epithelial cells lining the trachea and bronchi. Expression in lung is mainly restricted to bronchi, submucosal glands of the trachea, and tracheal epithelium, with little expression in terminal bronchioles.
  • 数据库链接：

    KEGG: mmu:68662

    STRING: 10090.ENSMUSP00000043325

    UniGene: Mm.22802