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  4. Recombinant Mouse Syntaxin-12 (Stx12), partial

Recombinant Mouse Syntaxin-12 (Stx12), partial

  • 中文名称：
    小鼠Stx12重组蛋白
  • 货号：
    CSB-YP861686MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Stx12重组蛋白
  • 货号：
    CSB-EP861686MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Stx12重组蛋白
  • 货号：
    CSB-EP861686MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Stx12重组蛋白
  • 货号：
    CSB-BP861686MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Stx12重组蛋白
  • 货号：
    CSB-MP861686MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Stx12
  • Uniprot No.：
  • 别名：
    Stx12; Syntaxin-12
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting.
  • 基因功能参考文献：
    1. STX13 acts as a fusion SNARE in melanosomal trafficking pathways. PMID: 26208634
    2. These data suggest that syntaxin13 translation is regulated by mTOR in injured neurons to promote axon regeneration. PMID: 24737317
    3. the developmentally regulated syntaxin 13 expression in various neuronal populations is consistent with its involvement in endocytic trafficking and neurite outgrowth. PMID: 12172780
    4. Potential role for Rlbp1 and Syntaxin 12 in ethanol preference in mice, a conclusion supported by the location of these genes in quantitative trait loci PMID: 15082940
    5. Syntaxin 12 has a role as a potential contributor to alcohol preference in mice PMID: 19107586

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  • 亚细胞定位：
    Endosome membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein. Endomembrane system; Single-pass type IV membrane protein; Cytoplasmic side. Early endosome membrane; Single-pass type IV membrane protein. Recycling endosome membrane; Single-pass type IV membrane protein.
  • 蛋白家族：
    Syntaxin family
  • 数据库链接：

    KEGG: mmu:100226

    STRING: 10090.ENSMUSP00000030698

    UniGene: Mm.28237