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  4. Recombinant Mouse U3 small nucleolar RNA-associated protein 14 homolog B (Utp14b)

Recombinant Mouse U3 small nucleolar RNA-associated protein 14 homolog B (Utp14b)

  • 中文名称：
    小鼠Utp14b重组蛋白
  • 货号：
    CSB-YP732282MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Utp14b重组蛋白
  • 货号：
    CSB-EP732282MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Utp14b重组蛋白
  • 货号：
    CSB-EP732282MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Utp14b重组蛋白
  • 货号：
    CSB-BP732282MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Utp14b重组蛋白
  • 货号：
    CSB-MP732282MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Utp14b
  • Uniprot No.：
  • 别名：
    Utp14b; JsdU3 small nucleolar RNA-associated protein 14 homolog B; Juvenile spermatogonial depletion protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-756
  • 氨基酸序列
    MNMARNVTDL LALSQQEELV DLPENYPLST SEDEGDSDGE GKRQKLLEAV SSLGRKNKWK LAERSEASRM VSEFNVTSEG SGEKLVLSDL LGSATALSSV AAVKKQLHRV KSKTLTPPLN KEEADRALRE AAFSKTSQML SRWDPVVLKN RQAEQLIFPM EKEPPAVAPI EHVFTDWKVR TPLEQEVFNL LHKNKQPVTD PLLTPVETAS IRAMSLEEAK IRRAELQRMR ALQSYYEARA RREKRIKSKK YHRALKKGKA KKALKEFEEL WKDCPNAALQ ELEKMEKARM TERMSLKHQG SGKWAKSKAI MAKYDPEARK AMQEQLAKNR ELTQKLQVVS ESEEEDGCTE EGIVSVSHGM DDLQMNADGV NPWMLSSCNS NAKRGEIKTD PEQMPEFVAH VSSESEGDER PVAEELVLKE RSFQERVDPN NAKLMDGQET EDSDSQEVLQ KLNKESHQSD NQKVSSEENV LHIQREDLAS EKLLVLQRLE RAHVLEQQGE LSKEEHYPKK GLSRPLLKGD WKEMKPLTNP DASGGKKKKE QMIDLRNLLT ANSSPVRSLA VPTIQQLEDE VETDHKQLIR EAFAGDDVIR EFLKEKREAI ETNKPKDLDL SLPGWGEWVG MGLKPSAKKR RRFLIKAPES SPRKDKNLPN VIISEKRNIH AAAHQVRALP HPFTHQQQFE RTIQNPIGYM WNTQRTFQKL TVPKVGTKLG HIIKPIKAEN VGYCSSTRSD LSILQSSQKC LSRKQQKQLK KLSSAD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis.
  • 基因功能参考文献：
    1. inhibition of spermatogonial differentiation in jsd mice is a result of testosterone acting through the AR only at scrotal temperatures PMID: 16627582
    2. The novel cell-type-specific promoter for Utp14b likely evolved later, as the protein may have acquired a germ cell-specific function in spermatid development. PMID: 17291484
    3. In adult male mice homozygous for the juvenile spermatogonial depletion (Utp14b jsd) mutation in the Utp14b gene, type A spermatogonia proliferate but undergo apoptosis before differentiation. PMID: 18356279
  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    UTP14 family
  • 组织特异性：
    Expressed predominantly in germ cells of the testis; weakly expressed in brain.
  • 数据库链接：

    KEGG: mmu:195434

    STRING: 10090.ENSMUSP00000052149

    UniGene: Mm.276016